Academic Journal
Decarboxylative 1,3-dipolar cycloaddition of amino acids for the synthesis of heterocyclic compounds
| العنوان: | Decarboxylative 1,3-dipolar cycloaddition of amino acids for the synthesis of heterocyclic compounds |
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| المؤلفون: | Xiaofeng Zhang, Xiaoming Ma, Wei Zhang |
| المصدر: | Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 1677-1693 (2023) |
| بيانات النشر: | Beilstein-Institut, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Science LCC:Organic chemistry |
| مصطلحات موضوعية: | [3 + 2] cycloaddition, decarboxylation, 1,3-dipolar, double cycloaddition, one-pot synthesis, multicomponent reaction, semi-stabilized azomethine ylide, Science, Organic chemistry, QD241-441 |
| الوصف: | The [3 + 2] cycloadditions of stabilized azomethine ylides (AMYs) derived from amino esters are well-established. However, the reactions of semi-stabilized AMYs generated from decarboxylative condensation of α-amino acids with arylaldehydes are much less explored. The [3 + 2] adducts of α-amino acids could be used for a second [3 + 2] cycloaddition as well as for other post-condensation modifications. This article highlights our recent work on the development of α-amino acid-based [3 + 2] cycloaddition reactions of N–H-type AMYs in multicomponent, one-pot, and stepwise reactions for the synthesis of diverse heterocycles related to some bioactive compounds and natural products. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1860-5397 |
| Relation: | https://doaj.org/toc/1860-5397 |
| DOI: | 10.3762/bjoc.19.123 |
| URL الوصول: | https://doaj.org/article/31424f45d7da486da274332d3b1e59d1 |
| رقم الانضمام: | edsdoj.31424f45d7da486da274332d3b1e59d1 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 18605397 |
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| DOI: | 10.3762/bjoc.19.123 |