Academic Journal

Characterization of a Novel African Swine Fever Virus p72 Genotype II from Nigeria

التفاصيل البيبلوغرافية
العنوان: Characterization of a Novel African Swine Fever Virus p72 Genotype II from Nigeria
المؤلفون: Aruna Ambagala, Kalhari Goonewardene, Lindsey Lamboo, Melissa Goolia, Cassidy Erdelyan, Mathew Fisher, Katherine Handel, Oliver Lung, Sandra Blome, Jacqueline King, Jan Hendrik Forth, Sten Calvelage, Edward Spinard, Douglas P. Gladue, Charles Masembe, Adeyinka J. Adedeji, Toyin Olubade, Nanven A. Maurice, Hussaini G. Ularamu, Pam D. Luka
المصدر: Viruses, Vol 15, Iss 4, p 915 (2023)
بيانات النشر: MDPI AG, 2023.
سنة النشر: 2023
المجموعة: LCC:Microbiology
مصطلحات موضوعية: African swine fever, Nigeria, genotype II, West Africa, Microbiology, QR1-502
الوصف: African swine fever (ASF) is a high-consequence transboundary hemorrhagic fever of swine. It continues to spread across the globe causing socio-economic issues and threatening food security and biodiversity. In 2020, Nigeria reported a major ASF outbreak, killing close to half a million pigs. Based on the partial sequences of the genes B646L (p72) and E183L (p54), the virus responsible for the outbreak was identified as an African swine fever virus (ASFV) p72 genotype II. Here, we report further characterization of ASFV RV502, one of the isolates obtained during the outbreak. The whole genome sequence of this virus revealed a deletion of 6535 bp between the nucleotide positions 11,760–18,295 of the genome, and an apparent reverse complement duplication of the 5′ end of the genome at the 3′ end. Phylogenetically, ASFV RV502 clustered together with ASFV MAL/19/Karonga and ASFV Tanzania/Rukwa/2017/1 suggesting that the virus responsible for the 2020 outbreak in Nigeria has a South-eastern African origin.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1999-4915
Relation: https://www.mdpi.com/1999-4915/15/4/915; https://doaj.org/toc/1999-4915
DOI: 10.3390/v15040915
URL الوصول: https://doaj.org/article/a30bc689db574c71a775e3de1d36668e
رقم الانضمام: edsdoj.30bc689db574c71a775e3de1d36668e
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19994915
DOI:10.3390/v15040915