Academic Journal
Integration-free T cell-derived human induced pluripotent stem cells (iPSCs) from a healthy individual: WT-iPSC1
العنوان: | Integration-free T cell-derived human induced pluripotent stem cells (iPSCs) from a healthy individual: WT-iPSC1 |
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المؤلفون: | Munenari Itoh, Shiho Kawagoe, Hirotaka James Okano, Hidemi Nakagawa |
المصدر: | Stem Cell Research, Vol 17, Iss 1, Pp 22-24 (2016) |
بيانات النشر: | Elsevier, 2016. |
سنة النشر: | 2016 |
المجموعة: | LCC:Biology (General) |
مصطلحات موضوعية: | Biology (General), QH301-705.5 |
الوصف: | Expanded human T cells from a Japanese healthy male were used to generate integration-free induced pluripotent stem cells (iPSCs) by exogenous expression of four reprogramming factors, OCT3/4, SOX2, cMYC, KLF4, using Sendai virus vector (SeVdp). The authenticity of established iPSC line, WT-iPSC1, was confirmed by the expressions of stem cell markers and the differentiation capability into three germ layers. WT-iPSC1 may be a useful cell resource as a normal control for the comparative study using disease-specific iPSCs. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1873-5061 1876-7753 |
Relation: | http://www.sciencedirect.com/science/article/pii/S1873506116300332; https://doaj.org/toc/1873-5061; https://doaj.org/toc/1876-7753 |
DOI: | 10.1016/j.scr.2016.05.001 |
URL الوصول: | https://doaj.org/article/2fd09f866e714d4ba31611ccaf095979 |
رقم الانضمام: | edsdoj.2fd09f866e714d4ba31611ccaf095979 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 18735061 18767753 |
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DOI: | 10.1016/j.scr.2016.05.001 |