Academic Journal

Journey to the other side of the brain: asymmetry in patients with chronic mild or moderate traumatic brain injury

التفاصيل البيبلوغرافية
العنوان: Journey to the other side of the brain: asymmetry in patients with chronic mild or moderate traumatic brain injury
المؤلفون: David E Ross, John D Seabaugh, Jan M Seabaugh, Claudia Alvarez, Laura Peyton Ellis, Christopher Powell, Christopher Reese, Leah Cooper, Katherine Shepherd, for the Alzheimer's Disease Neuroimaging Initiative
المصدر: Concussion, Vol 8, Iss 1 (2023)
بيانات النشر: Future Medicine Ltd, 2023.
سنة النشر: 2023
المجموعة: LCC:Medical emergencies. Critical care. Intensive care. First aid
مصطلحات موضوعية: asymmetry, MRI, NeuroGage®, NeuroQuant®, traumatic brain injury (TBI), volumetry, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
الوصف: Aim: Patients with chronic mild or moderate traumatic brain injury have some regions of brain atrophy (including cerebral white matter) but even more regions of abnormal brain enlargement (including other cerebral regions). Hypothesis: Ipsilateral injury and atrophy cause the eventual development of contralateral compensatory hypertrophy. Materials & methods: 50 patients with mild or moderate traumatic brain injury were compared to 80 normal controls (n = 80) with respect to MRI brain volume asymmetry. Asymmetry-based correlations were used to test the primary hypothesis. Results: The group of patients had multiple regions of abnormal asymmetry. Conclusion: The correlational analyses supported the conclusion that acute injury to ipsilateral cerebral white matter regions caused atrophy, leading eventually to abnormal enlargement of contralateral regions due to compensatory hypertrophy.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2056-3299
Relation: https://doaj.org/toc/2056-3299
DOI: 10.2217/cnc-2022-0003
URL الوصول: https://doaj.org/article/2fbb956bc0f84517872bb5afb7698fa3
رقم الانضمام: edsdoj.2fbb956bc0f84517872bb5afb7698fa3
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20563299
DOI:10.2217/cnc-2022-0003