Academic Journal
Advances in Strain Improvement for the Production of ε-Poly-L-lysine
| العنوان: | Advances in Strain Improvement for the Production of ε-Poly-L-lysine |
|---|---|
| المؤلفون: | SUN Zilong, FU Jiaolong, WANG Yue, ZHOU Yunfeng, LI Boyan, QIAN Wei, BAI Jing, JU Xin, LI Liangzhi |
| المصدر: | Shipin Kexue, Vol 44, Iss 23, Pp 231-251 (2023) |
| بيانات النشر: | China Food Publishing Company, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Food processing and manufacture |
| مصطلحات موضوعية: | ε-poly-l-lysine, breeding, ribosome engineering, genetic engineering, streptomyces albulus, Food processing and manufacture, TP368-456 |
| الوصف: | ε-Poly-L-lysine (ε-PL) is a novel biopolymer consisting of 25–35 L-lysine residues, which is formed by the dehydration condensation of ε-NH2 and α-COOH. ε-PL possesses many excellent characteristics, such as antimicrobial activity, edibility, water solubility, biodegradability, thermostability and nontoxicity. As a natural and safe food preservative, ε-PL possesses many excellent advantages such as thermal stability, edibility, water solubility, degradability, and broad-spectrum antibacterial activity and has been successfully utilized in Japan, South Korea, the United States, China and other countries. ε-PL is usually produced by fermentation with Streptomyces albulus, and improving ε-PL-producing stains is crucial for enhancing ε-PL production and reducing costs. At present, researchers have obtained microbial strains capable of producing high levels of ε-PL by using physicochemical mutagenesis, ribosome engineering, genome shuffling, genetic engineering and other methods. This review introduces the mechanism of ε-PL biosynthesis and recent progress in strain improvement for the production of ε-PL, and gives an overview of the fermentation process of ε-PL. Finally, this review concludes with an outlook on future research directions. We hope that this review can help promote strain improvement for green biological manufacturing of ε-poly-L-lysine. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Chinese |
| تدمد: | 1002-6630 |
| Relation: | https://www.spkx.net.cn/fileup/1002-6630/PDF/2023-44-23-027.pdf; https://doaj.org/toc/1002-6630 |
| DOI: | 10.7506/spkx1002-6630-20221114-158 |
| URL الوصول: | https://doaj.org/article/2f22dc491a594b358075ce6f9dab0614 |
| رقم الانضمام: | edsdoj.2f22dc491a594b358075ce6f9dab0614 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 10026630 |
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| DOI: | 10.7506/spkx1002-6630-20221114-158 |