Academic Journal
Activity and safety profile of low-dose rituximab for the treatment of autoimmune cytopenias in adults
| العنوان: | Activity and safety profile of low-dose rituximab for the treatment of autoimmune cytopenias in adults |
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| المؤلفون: | Drew Provan, Tom Butler, Maria Laura Evangelista, Sergio Amadori, Adrian C. Newland, Roberto Stasi |
| المصدر: | Haematologica, Vol 92, Iss 12 (2007) |
| بيانات النشر: | Ferrata Storti Foundation, 2007. |
| سنة النشر: | 2007 |
| المجموعة: | LCC:Diseases of the blood and blood-forming organs |
| مصطلحات موضوعية: | Diseases of the blood and blood-forming organs, RC633-647.5 |
| الوصف: | We conducted a retrospective analysis of 11 consecutive patients with various autoimmune cytopenias who failed to respond to conventional treatments and received a fixed-dose regimen of rituximab (100 mg weekly for 4 consecutive weeks). Sustained complete responses were achieved in 4 out of 7 patients with idiopathic thrombocytopenic purpura and in 1 patient with autoimmune pancytopenia. A partial response was observed in 1 patient with autoimmune hemolytic anemia. The immunotherapy had no effect in 1 patient with pure red cell aplasia or in 1 patient with autoimmune neutropenia. No infusion-related or delayed toxicities attributable to rituximab were experienced by any of the patients. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0390-6078 1592-8721 |
| Relation: | https://haematologica.org/article/view/4672; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721 |
| DOI: | 10.3324/haematol.11709 |
| URL الوصول: | https://doaj.org/article/2e59b163a3f5484a81d6beec9a856c31 |
| رقم الانضمام: | edsdoj.2e59b163a3f5484a81d6beec9a856c31 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 03906078 15928721 |
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| DOI: | 10.3324/haematol.11709 |