التفاصيل البيبلوغرافية
| العنوان: |
A novel prognostic biomarker in progression free survival for patients with cervical cancer, glucose to c-reactive protein ratio (GCR) |
| المؤلفون: |
Mehmet Emin Buyukbayram, Zekeriya Hannarici, Aykut Turhan, Alperen Akansel Caglar, Pınar Çoban Esdur, Mehmet Bilici, Salim Basol Tekin, Burak Erdemci |
| المصدر: |
BMC Cancer, Vol 24, Iss 1, Pp 1-8 (2024) |
| بيانات النشر: |
BMC, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: |
Cervical cancer, glucose/c-reactivated protein ratio, Progression-free survival, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: |
Abstract Background Cervical cancer is a tumor with high morbidity and mortality. The importance of inflammatory and metabolic parameters affecting progression-free survival (PFS) and overall survival (OS) has been investigated more intensively recently. We aimed to investigate the effect of glucose/c-reactive protein (CRP) ratio [GCR], which shows these two parameters together, on PFS in cervical cancer. Methods We retrospectively included 90 patients with adenocarcinoma and squamous cell carcinoma of the cervix. The effects of clinical variables, inflammatory and glycemic parameters on PFS and OS were analyzed by Kaplan-Meier method. The data were compared with the healthy control group of 90 individuals using the independent t test. The effect of parameters on mortality was analyzed using ROC curves and cut off values were determined. Results Glucose, CRP, CRP/lymphocyte ratio (CLR) and GCR were statistically significant in predicting mortality (p |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1471-2407 |
| Relation: |
https://doaj.org/toc/1471-2407 |
| DOI: |
10.1186/s12885-024-12347-x |
| URL الوصول: |
https://doaj.org/article/dd2e5948d31e418c995f4eec39b22d56 |
| رقم الانضمام: |
edsdoj.2e5948d31e418c995f4eec39b22d56 |
| قاعدة البيانات: |
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