التفاصيل البيبلوغرافية
| العنوان: |
Merkel Cell Carcinoma Concomitant with Invasive Bowen's Disease: Immunohistochemical Investigation of Tumor-Infiltrating Leukocytes |
| المؤلفون: |
Hisayuki Tono, Taku Fujimura, Eimei Iwama, Yoshiyuki Kusakari, Sadanori Furudate, Yumi Kambayashi, Takahiro Haga, Akira Hashimoto, Setsuya Aiba |
| المصدر: |
Case Reports in Dermatology, Vol 7, Iss 1, Pp 1-6 (2015) |
| بيانات النشر: |
Karger Publishers, 2015. |
| سنة النشر: |
2015 |
| المجموعة: |
LCC:Dermatology |
| مصطلحات موضوعية: |
Invasive Bowenߣs disease, Merkel cell carcinoma, Tumor-infiltrating leukocytes, CD8, Caspase 3, Dermatology, RL1-803 |
| الوصف: |
Merkel cell carcinoma (MCC) is an aggressive, cutaneous, neuroendocrine carcinoma and, in rare cases, occurs with Bowen's disease (BD). In this report, we describe a case of MCC concurrent with invasive BD and compare the profiles of tumor-infiltrating leukocytes in the lesional skin of MCC and invasive BD. Interestingly, immunohistochemical study revealed significant numbers of CD8+ cells and caspase 3-expressing cells in the same areas of invasive BD and MCC. Our present case suggests that MCC concurrent with invasive BD might have a good prognosis because of the substantial number of CD8+ cells in the tumor. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1662-6567 |
| Relation: |
http://www.karger.com/Article/FullText/371732; https://doaj.org/toc/1662-6567 |
| DOI: |
10.1159/000371732 |
| URL الوصول: |
https://doaj.org/article/edd2d9b0a9a6428a859171e3f1a17a68 |
| رقم الانضمام: |
edsdoj.2d9b0a9a6428a859171e3f1a17a68 |
| قاعدة البيانات: |
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