Academic Journal
Proteinuria and Reduced Estimated Glomerular Filtration Rate are Independently Associated With Lower Cognitive Abilities in Apparently Healthy Community-Dwelling Elderly Men in Japan: A Cross-sectional Study
العنوان: | Proteinuria and Reduced Estimated Glomerular Filtration Rate are Independently Associated With Lower Cognitive Abilities in Apparently Healthy Community-Dwelling Elderly Men in Japan: A Cross-sectional Study |
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المؤلفون: | Akira Fujiyoshi, Katsuyuki Miura, Takayoshi Ohkubo, Naoko Miyagawa, Yoshino Saito, Itsuko Miyazawa, Akihiko Shiino, Aya Kadota, Sayaka Kadowaki, Takashi Hisamatsu, Sayuki Torii, Naoyuki Takashima, Ikuo Tooyama, Hirotsugu Ueshima |
المصدر: | Journal of Epidemiology, Vol 30, Iss 6, Pp 244-252 (2020) |
بيانات النشر: | Japan Epidemiological Association, 2020. |
سنة النشر: | 2020 |
المجموعة: | LCC:Medicine (General) |
مصطلحات موضوعية: | cognitive function, proteinuria, estimated glomerular filtration rate, chronic kidney disease (ckd), Medicine (General), R5-920 |
الوصف: | Background: The association of proteinuria and reduced estimated glomerular filtration rate (eGFR) with cognition needs more clarification. We cross-sectionally examined whether proteinuria and reduced eGFR, even in moderate stages, were independently associated with lower cognition in a community-based sample of elderly men. Methods: Our cohort initially comprised 1,094 men aged 40–79 years from a random sample from Shiga, Japan in 2006–2008. Of 853 men who returned for the follow-up examination (2009–2014), we analyzed 561 who were ≥65 years, free of stroke, and completed the Cognitive Abilities Screening Instrument (CASI) at follow-up (higher CASI scores [range 0 to 100] indicate better cognition). Proteinuria was assessed via dipstick. eGFR was calculated according to the Chronic Kidney Disease Epidemiology Collaboration Equation. Participants were divided into three groups either by eGFR (≥60, 59–40, and |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 0917-5040 1349-9092 |
Relation: | https://www.jstage.jst.go.jp/article/jea/30/6/30_JE20180258/_pdf; https://doaj.org/toc/0917-5040; https://doaj.org/toc/1349-9092 |
DOI: | 10.2188/jea.JE20180258 |
URL الوصول: | https://doaj.org/article/2d4443163350421eafbd2a07f9b6d27c |
رقم الانضمام: | edsdoj.2d4443163350421eafbd2a07f9b6d27c |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 09175040 13499092 |
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DOI: | 10.2188/jea.JE20180258 |