Academic Journal

Proteinuria and Reduced Estimated Glomerular Filtration Rate are Independently Associated With Lower Cognitive Abilities in Apparently Healthy Community-Dwelling Elderly Men in Japan: A Cross-sectional Study

التفاصيل البيبلوغرافية
العنوان: Proteinuria and Reduced Estimated Glomerular Filtration Rate are Independently Associated With Lower Cognitive Abilities in Apparently Healthy Community-Dwelling Elderly Men in Japan: A Cross-sectional Study
المؤلفون: Akira Fujiyoshi, Katsuyuki Miura, Takayoshi Ohkubo, Naoko Miyagawa, Yoshino Saito, Itsuko Miyazawa, Akihiko Shiino, Aya Kadota, Sayaka Kadowaki, Takashi Hisamatsu, Sayuki Torii, Naoyuki Takashima, Ikuo Tooyama, Hirotsugu Ueshima
المصدر: Journal of Epidemiology, Vol 30, Iss 6, Pp 244-252 (2020)
بيانات النشر: Japan Epidemiological Association, 2020.
سنة النشر: 2020
المجموعة: LCC:Medicine (General)
مصطلحات موضوعية: cognitive function, proteinuria, estimated glomerular filtration rate, chronic kidney disease (ckd), Medicine (General), R5-920
الوصف: Background: The association of proteinuria and reduced estimated glomerular filtration rate (eGFR) with cognition needs more clarification. We cross-sectionally examined whether proteinuria and reduced eGFR, even in moderate stages, were independently associated with lower cognition in a community-based sample of elderly men. Methods: Our cohort initially comprised 1,094 men aged 40–79 years from a random sample from Shiga, Japan in 2006–2008. Of 853 men who returned for the follow-up examination (2009–2014), we analyzed 561 who were ≥65 years, free of stroke, and completed the Cognitive Abilities Screening Instrument (CASI) at follow-up (higher CASI scores [range 0 to 100] indicate better cognition). Proteinuria was assessed via dipstick. eGFR was calculated according to the Chronic Kidney Disease Epidemiology Collaboration Equation. Participants were divided into three groups either by eGFR (≥60, 59–40, and
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0917-5040
1349-9092
Relation: https://www.jstage.jst.go.jp/article/jea/30/6/30_JE20180258/_pdf; https://doaj.org/toc/0917-5040; https://doaj.org/toc/1349-9092
DOI: 10.2188/jea.JE20180258
URL الوصول: https://doaj.org/article/2d4443163350421eafbd2a07f9b6d27c
رقم الانضمام: edsdoj.2d4443163350421eafbd2a07f9b6d27c
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:09175040
13499092
DOI:10.2188/jea.JE20180258