التفاصيل البيبلوغرافية
| العنوان: |
Characterization of a conductive hydrogel@Carbon fibers electrode as a novel intraneural interface |
| المؤلفون: |
Alice Giannotti, Ranieri Santanché, Ciro Zinno, Jacopo Carpaneto, Silvestro Micera, Eugenio Redolfi Riva |
| المصدر: |
Bioelectronic Medicine, Vol 10, Iss 1, Pp 1-14 (2024) |
| بيانات النشر: |
BMC, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Medical technology |
| مصطلحات موضوعية: |
Carbon fibers, Conductive hydrogel, Neural interface, Bioelectronic medicine, Medical technology, R855-855.5 |
| الوصف: |
Abstract Peripheral neural interfaces facilitate bidirectional communication between the nervous system and external devices, enabling precise control for prosthetic limbs, sensory feedback systems, and therapeutic interventions in the field of Bioelectronic Medicine. Intraneural interfaces hold great promise since they ensure high selectivity in communicating only with the desired nerve fascicles. Despite significant advancements, challenges such as chronic immune response, signal degradation over time, and lack of long-term biocompatibility remain critical considerations in the development of such devices. Here we report on the development and benchtop characterization of a novel design of an intraneural interface based on carbon fiber bundles. Carbon fibers possess low impedance, enabling enhanced signal detection and stimulation efficacy compared to traditional metal electrodes. We provided a 3D-stabilizing structure for the carbon fiber bundles made of PEDOT:PSS hydrogel, to enhance the biocompatibility between the carbon fibers and the nervous tissue. We further coated the overall bundles with a thin layer of elastomeric material to provide electrical insulation. Taken together, our results demonstrated that our electrode possesses adequate structural and electrochemical properties to ensure proper stimulation and recording of peripheral nerve fibers and a biocompatible interface with the nervous tissue. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2332-8886 |
| Relation: |
https://doaj.org/toc/2332-8886 |
| DOI: |
10.1186/s42234-024-00154-5 |
| URL الوصول: |
https://doaj.org/article/2c3a0d60db18484cb60a47330d304ea1 |
| رقم الانضمام: |
edsdoj.2c3a0d60db18484cb60a47330d304ea1 |
| قاعدة البيانات: |
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