Academic Journal
Plant metabolite 5-pentadecyl resorcinol is produced by the Amazonian fungus Penicillium sclerotiorum LM 5679
| العنوان: | Plant metabolite 5-pentadecyl resorcinol is produced by the Amazonian fungus Penicillium sclerotiorum LM 5679 |
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| المؤلفون: | L. A. Oliveira, M. M. Macedo, J. L. S. Rodrigues, E. S. Lima, P. G. Hamill, T. D. Dallas, M. P. Lima, E. S. Souza, J. E. Hallsworth, J. V. B. Souza |
| المصدر: | Brazilian Journal of Biology, Vol 82 (2021) |
| بيانات النشر: | Instituto Internacional de Ecologia, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Science LCC:Biology (General) LCC:Zoology LCC:Botany |
| مصطلحات موضوعية: | antifungal compounds, 5-pentadecyl resorcinol or cardol or adispostatin, bioprospecting ascomycete fungi, Penicillium sclerotiorum, secondary metabolites, tropical forest soil, Science, Biology (General), QH301-705.5, Zoology, QL1-991, Botany, QK1-989 |
| الوصف: | Abstract Since the classic studies of Alexander Flemming, Penicillium strains have been known as a rich source of antimicrobial substances. Recent studies have identified novel metabolites produced by Penicillium sclerotiorum that have antibacterial, antifouling and pharmaceutical activities. Here, we report the isolation of a P. sclerotiorum (LM 5679) from Amazonian soil and carry out a culture-based study to determine whether it can produce any novel secondary metabolite(s) that are not thus-far reported for this genus. Using a submerged culture system, secondary metabolites were recovered by solvent extract followed by thin-layer chromatography, nuclear magnetic resonance, and mass spectroscopy. One novel secondary metabolite was isolated from P. sclerotiorum (LM 5679); the phenolic compound 5-pentadecyl resorcinol widely known as an antifungal, that is produced by diverse plant species. This metabolite was not reported previously in any Penicillium species and was only found once before in fungi (that time, in a Fusarium). Here, we discuss the known activities of 5-pentadecyl resorcinol in the context of its mode-of-action as a hydrophobic (chaotropicity-mediated) stressor. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1678-4375 1519-6984 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842022000100222&tlng=en; https://doaj.org/toc/1678-4375 |
| DOI: | 10.1590/1519-6984.241863 |
| URL الوصول: | https://doaj.org/article/d2bfcf747f634ee189e889a10681dd98 |
| رقم الانضمام: | edsdoj.2bfcf747f634ee189e889a10681dd98 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16784375 15196984 |
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| DOI: | 10.1590/1519-6984.241863 |