Academic Journal
Early Magnetic Resonance Detection of Natalizumab-Related Progressive Multifocal Leukoencephalopathy in a Patient with Multiple Sclerosis
| العنوان: | Early Magnetic Resonance Detection of Natalizumab-Related Progressive Multifocal Leukoencephalopathy in a Patient with Multiple Sclerosis |
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| المؤلفون: | Guglielmo Manenti, Simone Altobelli, Marco Nezzo, Marco Antonicoli, Erald Vasili, Luca Neroni, Roberto Floris, Giovanni Simonetti |
| المصدر: | Case Reports in Radiology, Vol 2013 (2013) |
| بيانات النشر: | Wiley, 2013. |
| سنة النشر: | 2013 |
| المجموعة: | LCC:Medical physics. Medical radiology. Nuclear medicine |
| مصطلحات موضوعية: | Medical physics. Medical radiology. Nuclear medicine, R895-920 |
| الوصف: | Diagnosis of progressive multifocal leukoencephalopathy is usually based on the clinical presentation, on the demonstration of the brain lesions at the magnetic resonance imaging examination, and on the detection of the JC virus DNA in the cerebrospinal fluid with high sensitive polymerase chain reaction. The role of magnetic resonance imaging specifically in natalizumab-associated progressive multifocal leukoencephalopathy is strengthening, and it is gaining importance not only as an irreplaceable diagnostic tool but also as a surveillance and risk stratifying tool in treated patients. While other imaging techniques such as computed tomography lack sensitivity and specificity, magnetic resonance performed with morphological and functional sequences offers clinicians the possibility to early identify the stage of the disease and the emergence of an immune reconstitution inflammatory syndrome after natalizumab blood removal plasmapheresis. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2090-6862 2090-6870 |
| Relation: | https://doaj.org/toc/2090-6862; https://doaj.org/toc/2090-6870 |
| DOI: | 10.1155/2013/415873 |
| URL الوصول: | https://doaj.org/article/2b57be31895248b28c0ef0de67912e51 |
| رقم الانضمام: | edsdoj.2b57be31895248b28c0ef0de67912e51 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20906862 20906870 |
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| DOI: | 10.1155/2013/415873 |