التفاصيل البيبلوغرافية
| العنوان: |
The NLRP3 inflammasome – interleukin 1β axis in uveal melanoma |
| المؤلفون: |
Victor S. M. C. Correa, Nikolaos E. Efstathiou, Dimitrios P. Ntentakis, Zhen Yu, Toshio Narimatsu, Evangelos Gragoudas, Ivana K. Kim, Demetrios G. Vavvas |
| المصدر: |
FEBS Open Bio, Vol 13, Iss 3, Pp 545-555 (2023) |
| بيانات النشر: |
Wiley, 2023. |
| سنة النشر: |
2023 |
| المجموعة: |
LCC:Biology (General) |
| مصطلحات موضوعية: |
IL‐1, inflammasome, melanoma, NLRP3, skin, uveal, Biology (General), QH301-705.5 |
| الوصف: |
Uveal melanoma (UM) is the most common primary intraocular cancer in the adult population. Recent studies suggested that the NLRP3 inflammasome could be a therapeutic target for cutaneous melanoma (CM), but the role of NLRP3 in UM remains unknown. Here, we analyzed the NLRP3‐IL‐1β axis in 5 UM and 4 CM cell lines. Expression of NLRP3 mRNA in UM and CM was low, and expression in UM was lower than in CM (P |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2211-5463 |
| Relation: |
https://doaj.org/toc/2211-5463 |
| DOI: |
10.1002/2211-5463.13566 |
| URL الوصول: |
https://doaj.org/article/2b15d55188dc4325a2431a9d3f784964 |
| رقم الانضمام: |
edsdoj.2b15d55188dc4325a2431a9d3f784964 |
| قاعدة البيانات: |
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