Academic Journal

Is There a Need for Repetition of Skin Test in Childhood Allergic Diseases? Repetition of Skin Test and Allergic Diseases

التفاصيل البيبلوغرافية
العنوان: Is There a Need for Repetition of Skin Test in Childhood Allergic Diseases? Repetition of Skin Test and Allergic Diseases
المؤلفون: Mahmut Dogru, Ilknur Bostanci, Serap Ozmen, Tayfur Ginis, Handan Duman
المصدر: Allergology International, Vol 63, Iss 2, Pp 227-233 (2014)
بيانات النشر: Elsevier, 2014.
سنة النشر: 2014
المجموعة: LCC:Immunologic diseases. Allergy
مصطلحات موضوعية: allergen, allergic asthma, house dust mites, seasonal allergic rhinitis, skin prick test, Immunologic diseases. Allergy, RC581-607
الوصف: Background: Skin prick tests are widely used to determine sensitivity in allergic diseases. There is limited information about the natural history of skin sensitization tests and factors that affect them. It was aimed to determine the changes in skin test results and the factors affecting the reactivity of skin tests after a period of approximately four years in children with allergic disease. Methods: SPT of 170 patients among 2485 children with asthma and/or allergic rhinitis and/or atopic dermatitis, who underwent SPT between 2005 and 2007, were repeated after an interval of at least 3 years. Results: The mean age was 10.7±3.1 (5-18) years and 70% of the patients were male. In total 66 (39.0% of the study population) had a different skin tests result in follow-up. Alterations: loss of sensitivity in 18 (11%) patients, the formation of a new sensitivity in 37 (22%) patients, and 11 (6%) both gained and lost sensitization. The presence of atopy in the family, the presence of allergic rhinitis and IgE elevation significantly predicted the incidence of new sensitization. The presence of sensitization to multiple allergens significantly predicted the incidence of loss of sensitization. Conclusions: It is found that there was an alteration of sensitization in 4/10 children at the end of the average 4-year period. The presence of family atopy, the presence of allergic rhinitis and serum total IgE elevation were risk factors for the development of new sensitization. On the other hand sensitization to multiple allergens was risk factors for the loss of sensitization.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1323-8930
Relation: http://www.sciencedirect.com/science/article/pii/S1323893015300368; https://doaj.org/toc/1323-8930
DOI: 10.2332/allergolint.13-OA-0588
URL الوصول: https://doaj.org/article/2a9a85675348425a99d6cbcd5a599aee
رقم الانضمام: edsdoj.2a9a85675348425a99d6cbcd5a599aee
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:13238930
DOI:10.2332/allergolint.13-OA-0588