التفاصيل البيبلوغرافية
العنوان: |
Integrated High-Throughput Centrifugal Microfluidic Chip Device for Pathogen Detection On-Site |
المؤلفون: |
Shuyu Lu, Yuanzhan Yang, Siqi Cui, Anyi Li, Cheng Qian, Xiaoqiong Li |
المصدر: |
Biosensors, Vol 14, Iss 6, p 313 (2024) |
بيانات النشر: |
MDPI AG, 2024. |
سنة النشر: |
2024 |
المجموعة: |
LCC:Biotechnology |
مصطلحات موضوعية: |
centrifugal microfluidic chip, nucleic acid extraction, lamp, paraffin valve, hydrophobic valve, siphon valve, Biotechnology, TP248.13-248.65 |
الوصف: |
An integrated and high-throughput device for pathogen detection is crucial in point-of-care testing (POCT), especially for early diagnosis of infectious diseases and preventing the spread of infection. We developed an on-site testing platform that utilizes a centrifugal microfluidic chip and automated device to achieve high-throughput detection. The low-power (E. coli, our platform achieves a limit of detection (LOD) of 102 CFU/mL in 60 min. In summary, our active centrifugal microfluidic platform provides a solution for the integration of complex biological assays on turntables, with great potential in the application of point-of-care diagnosis. |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
2079-6374 |
Relation: |
https://www.mdpi.com/2079-6374/14/6/313; https://doaj.org/toc/2079-6374 |
DOI: |
10.3390/bios14060313 |
URL الوصول: |
https://doaj.org/article/a2a210ef074e4b539a23408e5d2feb2e |
رقم الانضمام: |
edsdoj.2a210ef074e4b539a23408e5d2feb2e |
قاعدة البيانات: |
Directory of Open Access Journals |