Academic Journal
The First Reported Case of Allogenic Hematopoietic Stem Cell Transplantation for CML Blast Phase (Monocytic Lineage) in the Tyrosine Kinase Inhibitor Era
| العنوان: | The First Reported Case of Allogenic Hematopoietic Stem Cell Transplantation for CML Blast Phase (Monocytic Lineage) in the Tyrosine Kinase Inhibitor Era |
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| المؤلفون: | Shinya Yamada, Kotaro Arita, Yukio Kondo, Shuichi Mizuta, Hirokazu Okumura |
| المصدر: | Case Reports in Oncology, Vol 15, Iss 2, Pp 535-540 (2022) |
| بيانات النشر: | Karger Publishers, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | chronic myeloid leukemia, chronic myeloid leukemia blast phase (monocytic lineage), tyrosine kinase inhibitor, hematopoietic stem cell transplantation, hyper-acute graft-versus-host disease, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Chronic myeloid leukemia (CML) blast phase (monocytic lineage) is extremely rare. A 39-year-old Japanese man was diagnosed with CML blast phase (monocytic lineage). T315I mutation was positive, ponatinib was initially started, and then, allogenic hematopoietic stem cell transplantation (allo-HSCT) was performed. Seven days after allo-HSCT, hyper-acute graft-versus-host disease developed, and medial temporal lobe encephalitis emerged 24 days after allo-HSCT. He was alive for over 1 year after allo-HSCT. This is the first case report of HSCT for CML blast phase (monocytic lineage) in tyrosine kinase inhibitor era. Further cases should be documented for effective treatment regimen and analysis of clinical features. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1662-6575 00052477 |
| Relation: | https://www.karger.com/Article/FullText/524770; https://doaj.org/toc/1662-6575 |
| DOI: | 10.1159/000524770 |
| URL الوصول: | https://doaj.org/article/2947f1c32a934d968b70899d48e5f40f |
| رقم الانضمام: | edsdoj.2947f1c32a934d968b70899d48e5f40f |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16626575 00052477 |
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| DOI: | 10.1159/000524770 |