التفاصيل البيبلوغرافية
| العنوان: |
Associations of an overall healthy lifestyle with the risk of metabolic dysfunction-associated fatty liver disease |
| المؤلفون: |
Caimei Yuan, Chengjing Zhang, Xin Geng, Chengwu Feng, Yang Su, Yinfan Wu, Ying Wang, Li Chen, Qiurong Ding, Trudy Voortman, Hongyang Wang, Geng Zong |
| المصدر: |
BMC Public Health, Vol 24, Iss 1, Pp 1-12 (2024) |
| بيانات النشر: |
BMC, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Public aspects of medicine |
| مصطلحات موضوعية: |
Lifestyle score, Hepatic steatosis, Fatty liver disease, Overweight, Type 2 diabetes, Proton density fat fraction, Public aspects of medicine, RA1-1270 |
| الوصف: |
Abstract Background Metabolic dysfunction-associated fatty liver disease (MAFLD) affects up to one-third of the global population. Since no approved pharmacotherapy for MAFLD is available, lifestyle modification remains the cornerstone of clinical care. Our study aims to evaluate the association of an overall healthy lifestyle with MAFLD risk. Methods We conducted an analysis of 327,387 participants from UK biobank. An overall healthy lifestyle score including six evidence-based lifestyles (diet, alcohol consumption, physical activity, sedentary behavior, sleep, and smoking) was assessed by questionnaires. MAFLD and its subtypes were diagnosed by blood biochemistry, ICD codes, and medication information from touchscreen and verbal interview. The prevalence ratios (PRs) and risk ratios (RRs) were estimated by Poisson regression models with robust variance. Results In the cross-sectional analysis, the PR (95% CI) was 0.83 (0.83 to 0.84) for MAFLD, and 0.83 (0.83 to 0.84) for MAFLD-overweight/obesity (MAFLD-O), 0.68 (0.66 to 0.70) for MAFLD-lean/normal weight and metabolic dysfunction (P-value for heterogeneity |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1471-2458 |
| Relation: |
https://doaj.org/toc/1471-2458 |
| DOI: |
10.1186/s12889-024-20663-x |
| URL الوصول: |
https://doaj.org/article/29093386d0fe4862996b2d973ec24766 |
| رقم الانضمام: |
edsdoj.29093386d0fe4862996b2d973ec24766 |
| قاعدة البيانات: |
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