Academic Journal
SRXN1 blood levels negatively correlate with hippocampal atrophy and cognitive decline [version 1; peer review: 2 approved]
| العنوان: | SRXN1 blood levels negatively correlate with hippocampal atrophy and cognitive decline [version 1; peer review: 2 approved] |
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| المؤلفون: | Bogdan Ovidiu Popescu, Maria Dobre, Luiza Spiru, Catalina Tudose, Ioana Cracana, Catalina Anca Cucos, Gabriela Niculescu, Gina Manda, Elena Milanesi |
| المصدر: | F1000Research, Vol 11 (2022) |
| بيانات النشر: | F1000 Research Ltd, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | SRXN1, MRI, blood, Cognitive decline, eng, Medicine, Science |
| الوصف: | Introduction: Cognitive decline, correlating with hippocampal atrophy, characterizes several neurodegenerative disorders having a background of low-level chronic inflammation and oxidative stress. Methods: In this cross-sectional study, we examined how cognitive decline and hippocampal subfields volume are associated with the expression of redox and inflammatory genes in peripheral blood. We analyzed 34 individuals with different cognitive scores according to Mini-Mental State Examination, corrected by age and education (adjMMSE). We identified a group presenting cognitive decline (CD) with adjMMSE |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2046-1402 |
| Relation: | https://f1000research.com/articles/11-114/v1; https://doaj.org/toc/2046-1402 |
| DOI: | 10.12688/f1000research.76191.1 |
| URL الوصول: | https://doaj.org/article/28f1aa4e3dbf43b18874dd664beeff47 |
| رقم الانضمام: | edsdoj.28f1aa4e3dbf43b18874dd664beeff47 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20461402 |
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| DOI: | 10.12688/f1000research.76191.1 |