Academic Journal

Clinical characteristics and treatment outcomes of severe (ICU) COVID-19 patients in Saudi Arabia: A single centre study

التفاصيل البيبلوغرافية
العنوان: Clinical characteristics and treatment outcomes of severe (ICU) COVID-19 patients in Saudi Arabia: A single centre study
المؤلفون: Saleh Alghamdi
المصدر: Saudi Pharmaceutical Journal, Vol 29, Iss 10, Pp 1096-1101 (2021)
بيانات النشر: Elsevier, 2021.
سنة النشر: 2021
المجموعة: LCC:Therapeutics. Pharmacology
مصطلحات موضوعية: Coronavirus, COVID-19, Antibiotics, Hydroxychloroquine, Intensive care unit, Saudi Arabia, Therapeutics. Pharmacology, RM1-950
الوصف: Background: There is limited information describing the presenting features and treatment outcomes of intensive care unit (ICU) patients with coronavirus disease 2019 (COVID-19) in Saudi Arabia. Objective: To investigates the clinical, epidemiological, laboratory, radiological, vital signs and treatment characteristics/outcomes of severe (ICU) COVID-19 patients in Albaha region, Saudi Arabia. Methods: A retrospective cohort study was conducted from 01 April 2020 to 31 August 2020 involving files review of 171 patients admitted to the ICU of a COVID-19 treatment centre as a result of severe symptoms. Results: Around a third of the ICU patients admitted were over 66 years of age, 59.6% males, 45% diabetics, 39% hypertensive, 25.7% smokers. Patients had symptoms such as 79% fever, 78% cough, 75% headache, 59% sore throat, 57% runny nose, and 75% cough. More than half of the patients had 0.5 u/ml) were the most significant laboratory results. The median stay in the hospital ranged from 4 to 15.6 days, and the ICU time ranged from 4 to 12.7 days. Approximately 29% of patients received antiviral, antimalarial, and antibiotic treatment, while 27.5% of patients received antibiotics and antimalarial therapy alone. Incorporating hydroxychloroquine in treatment protocols did not improve patients’ outcomes. Conclusions: Older age and cardio-metabolic comorbidities increase the risks of sever COVID-19. Different treatment protocols fail to improve mortality rates and urgent efforts are required to prevent the disease and reduce its severity.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1319-0164
Relation: http://www.sciencedirect.com/science/article/pii/S1319016421001559; https://doaj.org/toc/1319-0164
DOI: 10.1016/j.jsps.2021.08.008
URL الوصول: https://doaj.org/article/28b56abe4f394c50a0c591e1d175755b
رقم الانضمام: edsdoj.28b56abe4f394c50a0c591e1d175755b
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:13190164
DOI:10.1016/j.jsps.2021.08.008