Academic Journal
Synthesis and Antimicrobial Activity of New Benzimidazole derivatives Bearing Five-Membered Heterocyclic Moieties
العنوان: | Synthesis and Antimicrobial Activity of New Benzimidazole derivatives Bearing Five-Membered Heterocyclic Moieties |
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المؤلفون: | Ammar Ferman Abbood, Ahmed M. Abdula, Ghosoun Laftaa Mohsen, Younis Baqi |
المصدر: | Al-Mustansiriyah Journal of Science, Vol 32, Iss 4, Pp 26-33 (2021) |
بيانات النشر: | Mustansiriyah University, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Science |
مصطلحات موضوعية: | benzimidazol, pyrazoline, isoxazoline, antimicrobial, Science |
الوصف: | A new series of 2-substituted-1H-benzimidazol as potentially antimicrobial agents were designed, synthesized and characterized by IR, 1H-NMR and Mass spectra. The synthesized compounds were in vitro screened against Escherichia coli, Klebsiella spp. (gram negative), Staphylococcus aureus, Staphylococcus epidermidis (gram positive) as well as Candida albicans. The in vitro biological evaluation revealed that some of the target compounds exerted good antimicrobial activity. Noticeably, compound 11 exhibited promising activity against Staphylococcus aureus and Klebseilla SPP at 1 mg/mL concentration. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1814-635X 2521-3520 |
Relation: | http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/992; https://doaj.org/toc/1814-635X; https://doaj.org/toc/2521-3520 |
DOI: | 10.23851/mjs.v32i4.992 |
URL الوصول: | https://doaj.org/article/28a7acd3d68b4d5bbc84f65f5975dc73 |
رقم الانضمام: | edsdoj.28a7acd3d68b4d5bbc84f65f5975dc73 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 1814635X 25213520 |
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DOI: | 10.23851/mjs.v32i4.992 |