التفاصيل البيبلوغرافية
| العنوان: |
Understanding the Impact of COVID-19 on Angioplasty Service and Outcome of Patients Treated for Chronic Limb-Threatening Ischaemia: A Single-Centre Retrospective Cohort Study |
| المؤلفون: |
Alexander D. Rodway, Jenny Harris, Lydia Hanna, Charlotte Allan, Felipe Pazos Casal, Ciara Giltinan, Ali Dehghan-Nayeri, Andre Santos, Martin B. Whyte, Nikolaos Ntagiantas, Ivan Walton, Richard Brown, Simon S. Skene, Ajay Pankhania, Benjamin C. T. Field, Gary D. Maytham, Christian Heiss |
| المصدر: |
Biomedicines, Vol 11, Iss 7, p 2034 (2023) |
| بيانات النشر: |
MDPI AG, 2023. |
| سنة النشر: |
2023 |
| المجموعة: |
LCC:Biology (General) |
| مصطلحات موضوعية: |
day-case angioplasty, critical limb ischaemia, peripheral artery disease, Biology (General), QH301-705.5 |
| الوصف: |
We evaluated the impact of COVID-19 restriction on the angioplasty service and outcome of chronic limb-threatening ischaemia (CLTI) patients undergoing lower-limb angioplasty in a UK secondary care setting. Consecutive patients were analysed retrospectively. Pre-COVID-19 (08/2018–02/2020), 106 CLTI patients (91% Fontaine 4; 60% diabetes mellitus) and during COVID-19 (03/2020–07/2021) 94 patients were treated (86% Fontaine 4; 66% diabetes mellitus). While the average monthly number of patients treated did not change, the proportion of day cases significantly increased (53% to 80%), and hospitalised patients decreased. Patients treated in ≤14/5 days after referral significantly increased to 64/63%. Kaplan–Meier survival analysis (30-day/1-year) showed that neither wound healing nor mortality were significantly changed during COVID-19. In day cases, 1-year but not 30-day major amputations significantly increased, and clinically driven target-lesion revascularisation decreased during COVID-19. One-year mortality was significantly worse in hospitalised compared to day cases (14% vs. 43%) at similar wound healing rates (83% vs. 84%). The most frequent known cause of death was infectious disease (64%), while cardiovascular (21%) was less frequent. Despite COVID-19 restrictions, a safe and effective angioplasty service was maintained while shortening waiting times. Very high mortality rates in hospitalised patients may indicate that CLTI patients need to be referred and treated more aggressively earlier. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2227-9059 |
| Relation: |
https://www.mdpi.com/2227-9059/11/7/2034; https://doaj.org/toc/2227-9059 |
| DOI: |
10.3390/biomedicines11072034 |
| URL الوصول: |
https://doaj.org/article/2778bbbe9fcd4eb588094d582002a3b1 |
| رقم الانضمام: |
edsdoj.2778bbbe9fcd4eb588094d582002a3b1 |
| قاعدة البيانات: |
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