التفاصيل البيبلوغرافية
العنوان: |
Identification of putative causal loci in whole-genome sequencing data via knockoff statistics |
المؤلفون: |
Zihuai He, Linxi Liu, Chen Wang, Yann Le Guen, Justin Lee, Stephanie Gogarten, Fred Lu, Stephen Montgomery, Hua Tang, Edwin K. Silverman, Michael H. Cho, Michael Greicius, Iuliana Ionita-Laza |
المصدر: |
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021) |
بيانات النشر: |
Nature Portfolio, 2021. |
سنة النشر: |
2021 |
المجموعة: |
LCC:Science |
مصطلحات موضوعية: |
Science |
الوصف: |
Association analyses that capture rare and noncoding variants in whole genome sequencing data are limited by factors like statistical power. Here, the authors present KnockoffScreen, a statistical method using the knockoff framework to detect, localise and prioritise rare and common risk variants at genome-wide scale. |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-021-22889-4 |
URL الوصول: |
https://doaj.org/article/ecd27486fdc04053bfaf9a54c6671fc9 |
رقم الانضمام: |
edsdoj.27486fdc04053bfaf9a54c6671fc9 |
قاعدة البيانات: |
Directory of Open Access Journals |