Academic Journal

Identification of putative causal loci in whole-genome sequencing data via knockoff statistics

التفاصيل البيبلوغرافية
العنوان: Identification of putative causal loci in whole-genome sequencing data via knockoff statistics
المؤلفون: Zihuai He, Linxi Liu, Chen Wang, Yann Le Guen, Justin Lee, Stephanie Gogarten, Fred Lu, Stephen Montgomery, Hua Tang, Edwin K. Silverman, Michael H. Cho, Michael Greicius, Iuliana Ionita-Laza
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
بيانات النشر: Nature Portfolio, 2021.
سنة النشر: 2021
المجموعة: LCC:Science
مصطلحات موضوعية: Science
الوصف: Association analyses that capture rare and noncoding variants in whole genome sequencing data are limited by factors like statistical power. Here, the authors present KnockoffScreen, a statistical method using the knockoff framework to detect, localise and prioritise rare and common risk variants at genome-wide scale.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-021-22889-4
URL الوصول: https://doaj.org/article/ecd27486fdc04053bfaf9a54c6671fc9
رقم الانضمام: edsdoj.27486fdc04053bfaf9a54c6671fc9
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20411723
DOI:10.1038/s41467-021-22889-4