التفاصيل البيبلوغرافية
| العنوان: |
Cranberries and Cancer: An Update of Preclinical Studies Evaluating the Cancer Inhibitory Potential of Cranberry and Cranberry Derived Constituents |
| المؤلفون: |
Katherine M. Weh, Jennifer Clarke, Laura A. Kresty |
| المصدر: |
Antioxidants, Vol 5, Iss 3, p 27 (2016) |
| بيانات النشر: |
MDPI AG, 2016. |
| سنة النشر: |
2016 |
| المجموعة: |
LCC:Therapeutics. Pharmacology |
| مصطلحات موضوعية: |
cranberry, cancer, proanthocyanidin, quercetin, ursolic acid, Therapeutics. Pharmacology, RM1-950 |
| الوصف: |
Cranberries are rich in bioactive constituents reported to influence a variety of health benefits, ranging from improved immune function and decreased infections to reduced cardiovascular disease and more recently cancer inhibition. A review of cranberry research targeting cancer revealed positive effects of cranberries or cranberry derived constituents against 17 different cancers utilizing a variety of in vitro techniques, whereas in vivo studies supported the inhibitory action of cranberries toward cancers of the esophagus, stomach, colon, bladder, prostate, glioblastoma and lymphoma. Mechanisms of cranberry-linked cancer inhibition include cellular death induction via apoptosis, necrosis and autophagy; reduction of cellular proliferation; alterations in reactive oxygen species; and modification of cytokine and signal transduction pathways. Given the emerging positive preclinical effects of cranberries, future clinical directions targeting cancer or premalignancy in high risk cohorts should be considered. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2076-3921 |
| Relation: |
http://www.mdpi.com/2076-3921/5/3/27; https://doaj.org/toc/2076-3921 |
| DOI: |
10.3390/antiox5030027 |
| URL الوصول: |
https://doaj.org/article/25f9f2efeae7487e92e7e58952a2ac16 |
| رقم الانضمام: |
edsdoj.25f9f2efeae7487e92e7e58952a2ac16 |
| قاعدة البيانات: |
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