Academic Journal
Epidemiological profile and follow-up of patients with pulmonary disease by non-tuberculous mycobacteria in Baixada Santista area, São Paulo
| العنوان: | Epidemiological profile and follow-up of patients with pulmonary disease by non-tuberculous mycobacteria in Baixada Santista area, São Paulo |
|---|---|
| المؤلفون: | Andréa Gobetti Vieira Coelho, Ana Carolina Chiou, Heloisa da Silveira Paro Pedro, Susilene Maria Tonelli Nardi, Erica Chimara |
| المصدر: | Einstein (São Paulo), Vol 20 (2022) |
| بيانات النشر: | Instituto Israelita de Ensino e Pesquisa Albert Einstein, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | Lung diseases/diagnosis, Lung diseases/epidemiology, Nontuberculous mycobacteria, Opportunistic infections, Medicine |
| الوصف: | ABSTRACT Objective To present the frequency and species diversity of non-tuberculous mycobacteria, estimate the prevalence of non-tuberculous mycobacterial pulmonary disease, describe the epidemiological profile, and determine the follow-up of patients with non-tuberculous mycobacterial pulmonary disease living in a region with a high burden of tuberculosis. Methods This a retrospective cohort observational study using data records obtained from the Instituto Adolfo Lutz - Santos and from the São Paulo Sistema de Vigilância de Tuberculose do Estado de São Paulo in the period between 2000 and 2009. The studied variables were: socio-demographic characteristics, current and past history of tuberculosis, aspects related to diagnosis, and treatment and associated diseases. Results We included 319 non-tuberculous mycobacteria isolates in the study, corresponding to 257 patients. The species Mycobacterium kansasii (28.5%) and Mycobacterium fortuitum (16.6%) presented the higher occurrence. In 10.9% (24) of the patients, there was a criterion for confirming a case of pulmonary disease due to non-tuberculous mycobacteria. In relation to gender and age, male and individuals over 50 years old were the most frequent. Considering the confirmed cases, 47.8% had a past history of tuberculosis. Conclusion The lack of information about the cases is evident, since pulmonary disease due to non-tuberculous mycobacteria is not mandatory. The therapeutic regimen according to the identified species is fundamental for success in combating the infections caused by non-tuberculous mycobacteria. Besides that, information about the regional epidemiology of pulmonary disease caused by non-tuberculous mycobacteria and the search for associations with other comorbidities are important to establish the correct treatment. In order to improve surveillance of pulmonary diseases by non-tuberculous mycobacteria, we suggest the implantation of a sentinel surveillance and of population-based studies. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Portuguese |
| تدمد: | 2317-6385 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082022000100205&lng=en&tlng=en; http://www.scielo.br/pdf/eins/v20/2317-6385-eins-20-eAO5510.pdf; https://doaj.org/toc/2317-6385 |
| DOI: | 10.31744/einstein_journal/2022ao5510 |
| URL الوصول: | https://doaj.org/article/25d6188423ec4d6bb0b35cbf6f743b73 |
| رقم الانضمام: | edsdoj.25d6188423ec4d6bb0b35cbf6f743b73 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23176385 |
|---|---|
| DOI: | 10.31744/einstein_journal/2022ao5510 |