التفاصيل البيبلوغرافية
| العنوان: |
CVnCoV and CV2CoV protect human ACE2 transgenic mice from ancestral B BavPat1 and emerging B.1.351 SARS-CoV-2 |
| المؤلفون: |
Donata Hoffmann, Björn Corleis, Susanne Rauch, Nicole Roth, Janine Mühe, Nico Joel Halwe, Lorenz Ulrich, Charlie Fricke, Jacob Schön, Anna Kraft, Angele Breithaupt, Kerstin Wernike, Anna Michelitsch, Franziska Sick, Claudia Wylezich, Bernd Hoffmann, Moritz Thran, Andreas Thess, Stefan O. Mueller, Thomas C. Mettenleiter, Benjamin Petsch, Anca Dorhoi, Martin Beer |
| المصدر: |
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021) |
| بيانات النشر: |
Nature Portfolio, 2021. |
| سنة النشر: |
2021 |
| المجموعة: |
LCC:Science |
| مصطلحات موضوعية: |
Science |
| الوصف: |
Emerging SARS-CoV-2 variants with mutations in the spike protein raise concerns regarding vaccine efficacy. Here, the authors show that two spike encoding mRNA vaccines in preclinical and clinical development protect human ACE2 mice from the B.1.351 variant of concern and ancestral B BavPat1. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-021-24339-7 |
| URL الوصول: |
https://doaj.org/article/25c1d158976849108a4f7763b4e1755a |
| رقم الانضمام: |
edsdoj.25c1d158976849108a4f7763b4e1755a |
| قاعدة البيانات: |
Directory of Open Access Journals |
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