التفاصيل البيبلوغرافية
| العنوان: |
Antimicrobial Efficacy of a Portable UV-C-Based Coating Activation Device against Candida albicans Biofilm and SARS-CoV-2 as an Additional Feature: An In Vitro Study |
| المؤلفون: |
Adityakrisna Yoshi Putra Wigianto, Megumi Watanabe, Yuki Iwawaki, Takaharu Goto, Tamaki Otsuki, Tetsuo Ichikawa |
| المصدر: |
Hygiene, Vol 4, Iss 1, Pp 93-102 (2024) |
| بيانات النشر: |
MDPI AG, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Industrial medicine. Industrial hygiene |
| مصطلحات موضوعية: |
UV-C irradiation, MPC coating, Candida albicans, SARS-CoV-2, Industrial medicine. Industrial hygiene, RC963-969, Industrial hygiene. Industrial welfare, HD7260-7780.8 |
| الوصف: |
This in vitro study aimed to confirm the effect of the additional features of Kirei Keep Light (KKL), a commercial UV-C irradiation system that was originally created for coating the surface of removable dentures with photoreactive 2-methacryloyloxyethyl phosphorylcholine (MPC), on the antimicrobial efficacy aspect against Candida albicans biofilm on a denture base material (PMMA) and SARS-CoV-2. Materials and Methods: The antimicrobial efficacy on C. albicans biofilm was evaluated through quantitative (CFU) and qualitative (SEM images) analysis of three groups: no treatment (control), KKL, and immersion in a disinfectant solution, MCAE. The quantitative evaluation on SARS-CoV-2 was performed by comparing the untreated (control) group and the KKL group. Results: In comparison with the control group (2.39 × 106 CFU/mL), KKL irradiation resulted in a 91.01% reduction in C. albicans biofilm (2.15 × 105 CFU/mL), whereas for the MCAE group, this reduction was 99.98% (4.64 × 102 CFU/mL). The SEM image results also corroborate the CFU results, which showed that the fewest clean surfaces were found in the control, and this gradually increased with KKL and MCAE. SARS-CoV-2 inhibition, indicated by its TCID50 value, demonstrated that KKL almost completely inhibited SARS-CoV-2 infection and replication (99.99% reduction). Conclusion: KKL possesses antimicrobial efficacy on C. albicans biofilm on PMMA and SARS-CoV-2. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2673-947X |
| Relation: |
https://www.mdpi.com/2673-947X/4/1/6; https://doaj.org/toc/2673-947X |
| DOI: |
10.3390/hygiene4010006 |
| URL الوصول: |
https://doaj.org/article/a25b8e62a1a04aa89bb2cc11864a81f7 |
| رقم الانضمام: |
edsdoj.25b8e62a1a04aa89bb2cc11864a81f7 |
| قاعدة البيانات: |
Directory of Open Access Journals |