التفاصيل البيبلوغرافية
العنوان: |
Spatially resolved transcriptomic profiling of degraded and challenging fresh frozen samples |
المؤلفون: |
Reza Mirzazadeh, Zaneta Andrusivova, Ludvig Larsson, Phillip T. Newton, Leire Alonso Galicia, Xesús M. Abalo, Mahtab Avijgan, Linda Kvastad, Alexandre Denadai-Souza, Nathalie Stakenborg, Alexandra B. Firsova, Alia Shamikh, Aleksandra Jurek, Niklas Schultz, Monica Nistér, Christos Samakovlis, Guy Boeckxstaens, Joakim Lundeberg |
المصدر: |
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023) |
بيانات النشر: |
Nature Portfolio, 2023. |
سنة النشر: |
2023 |
المجموعة: |
LCC:Science |
مصطلحات موضوعية: |
Science |
الوصف: |
Spatial transcriptomics relies on RNA quality, which is variable and dependent on sample handling, storage, and/or intrinsic factors. Here, authors present a genome-wide spatial gene expression profiling method called RNA Rescue Spatial Transcriptomics (RRST), designed for the analysis of moderate to low quality fresh frozen tissue samples and demonstrate its robustness on 7 different tissue types. |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-023-36071-5 |
URL الوصول: |
https://doaj.org/article/2506fddc5b224664b99b677008788151 |
رقم الانضمام: |
edsdoj.2506fddc5b224664b99b677008788151 |
قاعدة البيانات: |
Directory of Open Access Journals |