Academic Journal

An isolated organ feasibility study of deformable self-assembled magnetic anastomosis rings for esophageal stenosis anastomosis

التفاصيل البيبلوغرافية
العنوان: An isolated organ feasibility study of deformable self-assembled magnetic anastomosis rings for esophageal stenosis anastomosis
المؤلفون: Miaomiao Zhang, Xuhe Zhao, Qiuye Zhong, Linxin Shen, Ruimin Gong, Yi Lyu, Xiaopeng Yan
المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
بيانات النشر: Nature Portfolio, 2024.
سنة النشر: 2024
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Magnetic surgery, Magnetic compression anastomosis, Esophageal stenosis, Y-Z deformable self-assembled magnetic anastomosis rings, Esophageal anastomosis, Medicine, Science
الوصف: Abstract Magnetic compression anastomosis (MCA) for esophageal stenosis requires the insertion of magnets through two channels, transoral and transgastrostomy. Herein, we designed a Y-Z deformable self-assembled magnetic anastomosis ring (Y-Z DSAMAR) for esophageal stricture anastomosis through the transoral passage only. We introduce a Y-Z DSAMAR and verify its feasibility for single-access esophageal stenosis anastomosis in isolated organs. We procured esophagi from 10 pigs. Next, we ligated the middle part of these esophagi with 7 − 0 silk to prepare an esophageal stenosis model. The linear Y-Z DSAMAR completed the deformation self-assembly and transitioned from its initial linear shape to a circular one while passing through the esophageal stenosis. The operation time, the success rate of the deformation self-assembly of Y-Z DSAMARs, and the successful MCA for esophageal stenosis were recorded. We successfully obtained a trapezoidal magnetic unit. Ten such magnetic units can self-assemble into a ring after the hard guide wire is withdrawn. The success rates for both self-assembly deformation and esophageal stenosis anastomosis were 93.33%, while that for esophageal stenosis anastomosis with successful deformation was 100%. Y-Z DSAMARs exhibit remarkable deformation-controllable characteristics. Further optimization of the operational procedure and verification through animal experiments are needed before they can be clinically applied.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2045-2322
Relation: https://doaj.org/toc/2045-2322
DOI: 10.1038/s41598-024-81856-3
URL الوصول: https://doaj.org/article/c24d7916cfb948a68d4a7ab59c802b49
رقم الانضمام: edsdoj.24d7916cfb948a68d4a7ab59c802b49
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20452322
DOI:10.1038/s41598-024-81856-3