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Nanoparticles derived from herbal preparations May represent a novel nucleic acid therapy

التفاصيل البيبلوغرافية
العنوان: Nanoparticles derived from herbal preparations May represent a novel nucleic acid therapy
المؤلفون: Tingle Feng, Waqas Ahmed, Talha Ahmed, Lukui Chen
المصدر: Interdisciplinary Medicine, Vol 2, Iss 2, Pp n/a-n/a (2024)
بيانات النشر: Wiley-VCH, 2024.
سنة النشر: 2024
المجموعة: LCC:Medical technology
LCC:Biotechnology
مصطلحات موضوعية: bencaosome, decoctosome, nanoparticle, nucleic acid delivery system, nucleic acid therapy, Medical technology, R855-855.5, Biotechnology, TP248.13-248.65
الوصف: Abstract A significant number of nucleic acid therapies have been approved, highlighting the vast potential of nucleic acid therapeutics. Although numerous delivery strategies have been investigated, and progress has been made in nucleic acid delivery systems, the oral delivery route still presents a significant obstacle. Recently, a novel and promising force in oral nucleic acid delivery has emerged, namely Decoctosomes and Bencaosomes, obtained from the decoction of natural herbs, which refers to boiled Chinese herbal medicines. The active components of Decoctosomes include small molecules, peptides, and small RNAs (sRNAs). sRNAs were the first targets of extensive research. Additionally, Bencaosomes have been proven effective in several disease mouse models as artificially enhanced decoctosome products. This perspective summarizes the development and possible future directions of Decoctosomes and Bencaosomes, two varieties of nanoparticles that may open the door to new possibilities in nucleic acid therapy.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2832-6245
Relation: https://doaj.org/toc/2832-6245
DOI: 10.1002/INMD.20230029
URL الوصول: https://doaj.org/article/c24d5bf80cab482fbcf926a60df5201e
رقم الانضمام: edsdoj.24d5bf80cab482fbcf926a60df5201e
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:28326245
DOI:10.1002/INMD.20230029