التفاصيل البيبلوغرافية
| العنوان: |
Restoring Shank3 in the rostral brainstem of shank3ab−/− zebrafish autism models rescues sensory deficits |
| المؤلفون: |
Robert A. Kozol, David M. James, Ivan Varela, Sureni H. Sumathipala, Stephan Züchner, Julia E. Dallman |
| المصدر: |
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021) |
| بيانات النشر: |
Nature Portfolio, 2021. |
| سنة النشر: |
2021 |
| المجموعة: |
LCC:Biology (General) |
| مصطلحات موضوعية: |
Biology (General), QH301-705.5 |
| الوصف: |
Robert Kozol et al. developed two zebrafish Shank3 models to characterize the basis of sensorimotor deficits, which are a consistent feature in SHANK3-deficient human patients (Phelan-McDermid Syndrome). Their results suggest that hindbrain regions require Shank3 for normal responses to light, and provide further insight toward the biology of sensory deficits in Shank3 mutants. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2399-3642 |
| Relation: |
https://doaj.org/toc/2399-3642 |
| DOI: |
10.1038/s42003-021-02920-6 |
| URL الوصول: |
https://doaj.org/article/237a847199fe47c8b05031a8f8390531 |
| رقم الانضمام: |
edsdoj.237a847199fe47c8b05031a8f8390531 |
| قاعدة البيانات: |
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