التفاصيل البيبلوغرافية
| العنوان: |
Study on Immune Enhancement and Toxicological Evaluation of an Antioxidant Supplement |
| المؤلفون: |
Hui YANG, Jinwu ZHANG, Guangyan LI, Zeyuan DENG |
| المصدر: |
Shipin gongye ke-ji, Vol 45, Iss 13, Pp 300-307 (2024) |
| بيانات النشر: |
The editorial department of Science and Technology of Food Industry, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Food processing and manufacture |
| مصطلحات موضوعية: |
antioxidant supplement, astaxanthin, bee pollen extract, selenium-enriched yeast, immunity, toxicological evaluation, Food processing and manufacture, TP368-456 |
| الوصف: |
To study the immunomodulatory effects and safety of an antioxidant supplement composed primarily of Haematococcus pluvialis, selenium-enriched yeast, bee pollen extract, and vitamin E. Three different dosages (0.1, 0.2, and 0.4 g/kg bw) were administered via gavage once daily for 30 days in mice. The impact of this antioxidant supplement was observed on various parameters, including spleen index, thymus index, splenic lymphocyte transformation activity, delayed-type hypersensitivity, antibody-producing cell levels, hemolytic complement 50 (HC50), carbon clearance rate, phagocytic activity of macrophages, and natural killer cell activity. The potential carcinogenicity of the test materials, and their genotoxic effects on cells and the reproductive system were assessed through the Ames test, bone marrow micronucleus assay, and mouse sperm abnormality test, respectively. Subacute toxicity was investigated through a 30 day feeding trial. Results showed that compared to the control group, the middle and high-dosage groups exhibited significant increase in OD difference by 10.32% (P |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
Chinese |
| تدمد: |
1002-0306 |
| Relation: |
https://doaj.org/toc/1002-0306 |
| DOI: |
10.13386/j.issn1002-0306.2023080146 |
| URL الوصول: |
https://doaj.org/article/e1fc2d29f2014eceb425774672bbf246 |
| رقم الانضمام: |
edsdoj.1fc2d29f2014eceb425774672bbf246 |
| قاعدة البيانات: |
Directory of Open Access Journals |