التفاصيل البيبلوغرافية
العنوان: |
Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities |
المؤلفون: |
Thomas Kruse, Caroline Benz, Dimitriya H. Garvanska, Richard Lindqvist, Filip Mihalic, Fabian Coscia, Raviteja Inturi, Ahmed Sayadi, Leandro Simonetti, Emma Nilsson, Muhammad Ali, Johanna Kliche, Ainhoa Moliner Morro, Andreas Mund, Eva Andersson, Gerald McInerney, Matthias Mann, Per Jemth, Norman E. Davey, Anna K. Överby, Jakob Nilsson, Ylva Ivarsson |
المصدر: |
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
بيانات النشر: |
Nature Portfolio, 2021. |
سنة النشر: |
2021 |
المجموعة: |
LCC:Science |
مصطلحات موضوعية: |
Science |
الوصف: |
Many interactions between viral and host proteins are mediated by short peptide motifs. Here, using a phage-based viral peptide library, the authors identify 269 peptide-based interactions for 18 coronaviruses, including an interaction between SARS-CoV-2 N and G3BP1/2 that affects stress granules. |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-021-26498-z |
URL الوصول: |
https://doaj.org/article/1f444706eff944aca145f8ed28412f90 |
رقم الانضمام: |
edsdoj.1f444706eff944aca145f8ed28412f90 |
قاعدة البيانات: |
Directory of Open Access Journals |