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Which factors affect the live birth outcome of the first single euploid frozen-thawed blastocyst transfer in couples with balanced chromosomal translocations?

التفاصيل البيبلوغرافية
العنوان: Which factors affect the live birth outcome of the first single euploid frozen-thawed blastocyst transfer in couples with balanced chromosomal translocations?
المؤلفون: Ruixiao Zhang, Yahui Hu, Chenchen Cui, Cuilian Zhang
المصدر: Frontiers in Endocrinology, Vol 15 (2024)
بيانات النشر: Frontiers Media S.A., 2024.
سنة النشر: 2024
المجموعة: LCC:Diseases of the endocrine glands. Clinical endocrinology
مصطلحات موضوعية: balanced chromosomal translocations, preimplantation genetic testing for structural rearrangements (PGT-SR), euploid, frozen-thawed blastocyst transfer, live birth, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
الوصف: ObjectiveThe objective of this study is to investigate the factors that influence the live birth rate (LBR) of the first single euploid frozen-thawed blastocyst transfer (FBT) cycles after preimplantation genetic testing for structural rearrangements (PGT-SR) in couples with balanced chromosomal translocations (BCT).DesignSingle center, retrospective and observational study.MethodsA total of 336 PGT-SR and the first single euploid FBT cycles between July 2016 and December 2022 were included in this study. The patients were divided into two groups according to the live birth outcomes. The parameters of the study population, controlled ovarian stimulation cycles, and FBT cycles were analyzed. Multivariable binary logistic regression was performed to find the factors that affected the LBR.ResultsThe percentage of blastocysts at developmental stage Day 5 compared to Day 6 (51.8% vs. 30.8%; P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1664-2392
Relation: https://www.frontiersin.org/articles/10.3389/fendo.2024.1378635/full; https://doaj.org/toc/1664-2392
DOI: 10.3389/fendo.2024.1378635
URL الوصول: https://doaj.org/article/1d75a3cc08734a50b98170cc640259ce
رقم الانضمام: edsdoj.1d75a3cc08734a50b98170cc640259ce
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:16642392
DOI:10.3389/fendo.2024.1378635