Academic Journal

Risk factors for the need for advanced care among prescription and over‐the‐counter drug overdose patients

التفاصيل البيبلوغرافية
العنوان: Risk factors for the need for advanced care among prescription and over‐the‐counter drug overdose patients
المؤلفون: Chie Tanaka, Takashi Tagami, Makihiko Nagano, Fumihiko Nakayama, Junya Kaneko, Masamune Kuno
المصدر: Acute Medicine & Surgery, Vol 11, Iss 1, Pp n/a-n/a (2024)
بيانات النشر: Wiley, 2024.
سنة النشر: 2024
المجموعة: LCC:Medical emergencies. Critical care. Intensive care. First aid
مصطلحات موضوعية: acetaminophen, advanced care, alcohol, overdose, paracetamol, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
الوصف: Abstract Aim Prescription drug and over‐the‐counter (OTC) drug overdose is a major problem in emergency departments in Japan, and some need advanced care which is more than observation. We aimed to identify the prehospital risk factors for the need of advanced care among overdose patients. Methods This was a single‐center retrospective cohort study. We included overdoses patients of prescription drugs or OTC drugs, who admitted to our hospital between 2016 and 2021. We grouped them into advanced care and non‐advanced care. The main outcome was the need for advanced care. We performed a multiple logistic regression analysis, calculated the PAV score (Paracetamol use, Alcohol use, abnormal Vital signs on scene) and performed a receiver operating characteristic (ROC) analysis. Results There were 229 subjects. The logistic regression analysis revealed that alcohol, paracetamol, and the abnormal vital signs on scene were associated with advanced care (alcohol‐odds ratio [OR]: 2.95; 95% confidence interval [CI]: 1.29–6.75; paracetamol‐OR: 5.47; 95% CI: 2.18–13.71; abnormal vital signs‐OR: 4.61, 95% CI: 2.07–10.27). The rate of advanced care in the high PAV score (2 and 3) group was statistically higher than that in the low PAV score (0–1) group (p = 0.04). Area under the ROC curve of the PAV score was 0.72 (95% CI, 0.65–0.80). Conclusion Alcohol, paracetamol use and abnormal vital signs on scene might be risk factors for advanced care among prescription drugs or OTC drugs overdose patients, and the PAV score may predict the need for advanced care.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2052-8817
Relation: https://doaj.org/toc/2052-8817
DOI: 10.1002/ams2.942
URL الوصول: https://doaj.org/article/1d5d4d4a80e449dc9f2e4f08f47a3937
رقم الانضمام: edsdoj.1d5d4d4a80e449dc9f2e4f08f47a3937
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20528817
DOI:10.1002/ams2.942