Academic Journal

Determination of tissue hypoxia by physicochemical approach in premature anemia

التفاصيل البيبلوغرافية
العنوان: Determination of tissue hypoxia by physicochemical approach in premature anemia
المؤلفون: Zeliha Özdemir, Birgin Törer, Deniz Hanta, Bilin Cetinkaya, Hande Gulcan, Aylin Tarcan
المصدر: Pediatrics and Neonatology, Vol 58, Iss 5, Pp 425-429 (2017)
بيانات النشر: Elsevier, 2017.
سنة النشر: 2017
المجموعة: LCC:Pediatrics
مصطلحات موضوعية: anemia, premature, Stewart method, transfusion, tissue hypoxia, Pediatrics, RJ1-570
الوصف: Anemia is a common problem in premature infants and its most rapid and effective therapy is erythrocyte transfusion. However, owing to inherent risks of transfusion in this population, transfusions should be administered only when adequate oxygen delivery to tissues is impaired. The aim of this study was to determine tissue acid levels using Stewart method in an attempt to evaluate the tissue oxygenation level and thereby the accuracy of transfusion timing. Methods: This study included 47 infants delivered at gestational age below 34 weeks who required erythrocyte transfusion for premature anemia. Strong ion gap (SIG), unmeasurable anions (UMA), tissue acid levels (TA), and Cl/Na ratios were calculated before and after transfusion. Results: The mean birth weight and gestational age of the study population were 1210 ± 365 g and 29.2 ± 2.7 weeks, respectively. Tissue acid levels were increased (TA ≥ 4) and tissue hypoxia developed in 10 (16.6%) of 60 erythrocyte transfusions administered according to the restrictive transfusion approach. The patients were divided into two groups according to tissue acid levels as low (
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1875-9572
Relation: http://www.sciencedirect.com/science/article/pii/S1875957217301055; https://doaj.org/toc/1875-9572
DOI: 10.1016/j.pedneo.2016.09.003
URL الوصول: https://doaj.org/article/1d58e51920f140398454f1a63982ebd6
رقم الانضمام: edsdoj.1d58e51920f140398454f1a63982ebd6
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:18759572
DOI:10.1016/j.pedneo.2016.09.003