التفاصيل البيبلوغرافية
| العنوان: |
Effect of a chemically-modified-curcumin on dental resin biodegradation |
| المؤلفون: |
Qi Dai, Hsi-Ming Lee, Austin Giordano, Fu-Pen Chiang, Stephen G. Walker, Rafael Delgado-Ruiz, Francis Johnson, Lorne M. Golub, Ying Gu |
| المصدر: |
Frontiers in Oral Health, Vol 5 (2025) |
| بيانات النشر: |
Frontiers Media S.A., 2025. |
| سنة النشر: |
2025 |
| المجموعة: |
LCC:Dentistry |
| مصطلحات موضوعية: |
dental caries, dental cavities, dental caries susceptibility, fluoride, streptococcus mutans, doxycycline, Dentistry, RK1-715 |
| الوصف: |
IntroductionPrevious studies have shown Streptococcus mutans (S. mutans) esterase is a key mediator of dental composite biodegradation, which can contribute to recurrent caries. This study is to investigate the inhibitory effects of a novel Chemically-Modified-Curcumin (CMC 2.24) on esterase activities and related dental material biodegradation.MethodsDental adhesive materials and composite resins were incubated in S. mutans suspension with CMC 2.24 and other compounds, including doxycycline, Chemically-Modified-Tetracycline (CMT-3), and curcumin for 4 weeks. The pre- and post-incubation surface roughness were evaluated by either laser diffraction pattern and/or a 3D laser scanning microscope. Esterase enzyme inhibition assays were performed with the same test groups and activities were determined spectrophotometrically.ResultsAmong all experimental groups, CMC 2.24 significantly reduced surface roughness of dental composite (p |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2673-4842 |
| Relation: |
https://www.frontiersin.org/articles/10.3389/froh.2024.1506616/full; https://doaj.org/toc/2673-4842 |
| DOI: |
10.3389/froh.2024.1506616 |
| URL الوصول: |
https://doaj.org/article/1ca5cd84bef94cab835f6e770cbfdeb8 |
| رقم الانضمام: |
edsdoj.1ca5cd84bef94cab835f6e770cbfdeb8 |
| قاعدة البيانات: |
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