التفاصيل البيبلوغرافية
| العنوان: |
Investigating the effectiveness of intraoperative rapid parathyroid hormone assay in parathyroidectomy surgery in patients with secondary hyperparathyroidism |
| المؤلفون: |
Shirzad Nasiri, Seyed Mostafa Meshkati Yazd, Alireza Heshmati, Abnoos Mokhtari Ardekani, Masoud Najafi, Reza Shahriarirad |
| المصدر: |
BMC Endocrine Disorders, Vol 23, Iss 1, Pp 1-8 (2023) |
| بيانات النشر: |
BMC, 2023. |
| سنة النشر: |
2023 |
| المجموعة: |
LCC:Diseases of the endocrine glands. Clinical endocrinology |
| مصطلحات موضوعية: |
Secondary hyperparathyroidism, Parathyroidectomy, Intraoperative Rapid PTH, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
| الوصف: |
Abstract Introduction The use of Rapid Intraoperative parathyroid hormone (Io-PTH) assay during surgery in the management of parathyroid tissue in cases of primary hyperparathyroidism has been proven to be effective, while its utilization in secondary hyperparathyroidism (SHPT) has been rarely reported. In the present study, we aim to demonstrate the application of rapid Io-PTH assay in patients with SHPT following chronic kidney disease undergoing parathyroidectomy surgery. Method In this prospective study, five blood samples were taken from patients undergoing parathyroidectomy and upper thymectomy. Among the samples, two were pre-excision, including prior to the first incision, after exploration, and before parathyroids resection. Two additional samples were taken 10 and 20 min after the excision of the parathyroid glands. Another sample was collected twenty-four hours after the operation. Serum Calcium levels and PTH levels were evaluated and analyzed. Results We successfully managed SHPT in all 36 patients in our study. The patients included 24 males (66.7%) with a mean age of 49.97 ± 14.92. The mean PTH decreased significantly at 10 min, 20 min, one day, and six months after surgery (P |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1472-6823 |
| Relation: |
https://doaj.org/toc/1472-6823 |
| DOI: |
10.1186/s12902-023-01378-3 |
| URL الوصول: |
https://doaj.org/article/1bcd22f9fc1e4ec49fb325e15069064e |
| رقم الانضمام: |
edsdoj.1bcd22f9fc1e4ec49fb325e15069064e |
| قاعدة البيانات: |
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