Academic Journal

Supplementation of Lactobacillus plantarum ATCC14917 mitigates non-alcoholic fatty liver disease in high-fat-diet-fed rats

التفاصيل البيبلوغرافية
العنوان: Supplementation of Lactobacillus plantarum ATCC14917 mitigates non-alcoholic fatty liver disease in high-fat-diet-fed rats
المؤلفون: Xingjian Wen, Hejing Liu, Xiaoling Luo, Li Lui, Jiuyu Fan, Yajing Xing, Jia Wang, Xingfang Qiao, Na Li, Guixue Wang
المصدر: Frontiers in Microbiology, Vol 14 (2023)
بيانات النشر: Frontiers Media S.A., 2023.
سنة النشر: 2023
المجموعة: LCC:Microbiology
مصطلحات موضوعية: non-alcoholic fatty liver disease, Lactobacillus plantarum ATCC14917, oxidative stress, inflammation, gut microbiota, Microbiology, QR1-502
الوصف: Atherosclerosis and non-alcoholic fatty liver disease (NAFLD) have been increasing at an alarming rate worldwide. Many clinical studies have underlined the link between NAFLD and atherosclerosis. Our previous experiments have discovered that Lactobacillus (L.) plantarum ATCC14917 supplementation could decrease the progression of atherosclerotic lesion formation. In this study, we aimed to investigate the role of supplementation of L. plantarum ATCC14917 mitigates liver injury in rats fed with a high-fat diet (HFD, 45% kcal from fat). A total of 32 rats were randomly divided into four groups, including two intervention groups, who fed with HFD and administering either 1 × 107 or 1 × 109 colony forming units (CFU) of L. plantarum ATCC14917, the normal control group, and the HFD control group. The results showed that supplementation with low-dose and high-dose of L. plantarum ATCC14917 for 8 weeks could alleviate the body weight gain (p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1664-302X
Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2023.1146672/full; https://doaj.org/toc/1664-302X
DOI: 10.3389/fmicb.2023.1146672
URL الوصول: https://doaj.org/article/18fa0cc86dff4e2b88d4ca08b4838474
رقم الانضمام: edsdoj.18fa0cc86dff4e2b88d4ca08b4838474
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:1664302X
DOI:10.3389/fmicb.2023.1146672