التفاصيل البيبلوغرافية
العنوان: |
Supplementation of Lactobacillus plantarum ATCC14917 mitigates non-alcoholic fatty liver disease in high-fat-diet-fed rats |
المؤلفون: |
Xingjian Wen, Hejing Liu, Xiaoling Luo, Li Lui, Jiuyu Fan, Yajing Xing, Jia Wang, Xingfang Qiao, Na Li, Guixue Wang |
المصدر: |
Frontiers in Microbiology, Vol 14 (2023) |
بيانات النشر: |
Frontiers Media S.A., 2023. |
سنة النشر: |
2023 |
المجموعة: |
LCC:Microbiology |
مصطلحات موضوعية: |
non-alcoholic fatty liver disease, Lactobacillus plantarum ATCC14917, oxidative stress, inflammation, gut microbiota, Microbiology, QR1-502 |
الوصف: |
Atherosclerosis and non-alcoholic fatty liver disease (NAFLD) have been increasing at an alarming rate worldwide. Many clinical studies have underlined the link between NAFLD and atherosclerosis. Our previous experiments have discovered that Lactobacillus (L.) plantarum ATCC14917 supplementation could decrease the progression of atherosclerotic lesion formation. In this study, we aimed to investigate the role of supplementation of L. plantarum ATCC14917 mitigates liver injury in rats fed with a high-fat diet (HFD, 45% kcal from fat). A total of 32 rats were randomly divided into four groups, including two intervention groups, who fed with HFD and administering either 1 × 107 or 1 × 109 colony forming units (CFU) of L. plantarum ATCC14917, the normal control group, and the HFD control group. The results showed that supplementation with low-dose and high-dose of L. plantarum ATCC14917 for 8 weeks could alleviate the body weight gain (p |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
1664-302X |
Relation: |
https://www.frontiersin.org/articles/10.3389/fmicb.2023.1146672/full; https://doaj.org/toc/1664-302X |
DOI: |
10.3389/fmicb.2023.1146672 |
URL الوصول: |
https://doaj.org/article/18fa0cc86dff4e2b88d4ca08b4838474 |
رقم الانضمام: |
edsdoj.18fa0cc86dff4e2b88d4ca08b4838474 |
قاعدة البيانات: |
Directory of Open Access Journals |