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Antimicrobial resistance and virulence of subgingival staphylococci isolated from periodontal health and diseases

التفاصيل البيبلوغرافية
العنوان: Antimicrobial resistance and virulence of subgingival staphylococci isolated from periodontal health and diseases
المؤلفون: Ana Paula Vieira Colombo, Renata Martins do Souto, Lélia Lima Araújo, Laís Christina Pontes Espíndola, Fátima Aparecida R. R. Hartenbach, Clarissa Bichara Magalhães, Gabrielle da Silva Oliveira Alves, Talita Gomes Baêta Lourenço, Carina Maciel da Silva-Boghossian
المصدر: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
بيانات النشر: Nature Portfolio, 2023.
سنة النشر: 2023
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: Abstract The dysbiotic biofilm of periodontitis may function as a reservoir for opportunistic human pathogens of clinical relevance. This study explored the virulence and antimicrobial susceptibility of staphylococci isolated from the subgingival biofilm of individuals with different periodontal conditions. Subgingival biofilm was obtained from 142 individuals with periodontal health, 101 with gingivitis and 302 with periodontitis, and cultivated on selective media. Isolated strains were identified by mass spectrometry. Antimicrobial susceptibility was determined by disk diffusion. The mecA and virulence genes were surveyed by PCR. Differences among groups regarding species, virulence and antimicrobial resistance were examined by Chi-square, Kruskal–Wallis or Mann–Whitney tests. The overall prevalence of subgingival staphylococci was 46%, especially in severe periodontitis (> 60%; p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2045-2322
Relation: https://doaj.org/toc/2045-2322
DOI: 10.1038/s41598-023-38599-4
URL الوصول: https://doaj.org/article/1851830619d945828519a53ebe7efd92
رقم الانضمام: edsdoj.1851830619d945828519a53ebe7efd92
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20452322
DOI:10.1038/s41598-023-38599-4