Academic Journal
Associations between Maternal sFlt-1/PlGF Ratio and Perinatal and Neonatal Outcomes in Newborns Born to Mothers with Preeclampsia
| العنوان: | Associations between Maternal sFlt-1/PlGF Ratio and Perinatal and Neonatal Outcomes in Newborns Born to Mothers with Preeclampsia |
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| المؤلفون: | Hyo Ju Yang, Soo Yeon Lim, Hyun Soo Kim, Chang Won Choi, Young Hwa Jung |
| المصدر: | Neonatal Medicine, Vol 30, Iss 3, Pp 61-68 (2023) |
| بيانات النشر: | Korean Society of Neonatology, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Pediatrics |
| مصطلحات موضوعية: | sflt-1/plgf ratio, pre-eclampsia, premature, infant, morbidity, Pediatrics, RJ1-570 |
| الوصف: | Purpose The ratio of soluble fms-like tyrosine kinase 1 (sFlt-1) to placental growth factor (PlGF) is considered a predictive marker of preeclampsia. However, the relationship between the sFlt-1/PlGF ratio and perinatal and neonatal outcomes remains unknown. This study aimed to determine the associations of the sFlt-1/PlGF ratio with perinatal and neonatal outcomes in newborns born to mothers with preeclampsia. Methods This retrospective cohort study reviewed singleton neonates born to mothers with preeclampsia who underwent testing for the sFlt-1/PlGF ratio. We investigated the relationship between maternal sFlt-1/PlGF ratios and gestational age (GA), birth weight (Bwt), Bwt z-score, morbidities, and mortality of neonates born to mothers tested for the sFlt-1/PlGF ratio. Maternal sFlt-1/PlGF ratios examined within 30 days before delivery were used for analysis. Neonatal morbidities and mortality were investigated only in preterm infants born earlier than 32 weeks GA. Results A total of 225 neonates were included, of which 163 (72.4%) were preterm infants. GA (R=– 0.577, p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Korean |
| تدمد: | 2287-9412 2287-9803 |
| Relation: | http://neo-med.org/upload/pdf/nm-2023-30-3-61.pdf; https://doaj.org/toc/2287-9412; https://doaj.org/toc/2287-9803 |
| DOI: | 10.5385/nm.2023.30.3.61 |
| URL الوصول: | https://doaj.org/article/a159713dcb4a4351b350ea824f25ca46 |
| رقم الانضمام: | edsdoj.159713dcb4a4351b350ea824f25ca46 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 22879412 22879803 |
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| DOI: | 10.5385/nm.2023.30.3.61 |