Academic Journal

Assessing the psychometric properties of the French WHOQOL-HIV BREF within the ANRS CO3 Aquitaine Cohort’s QuAliV ancillary study

التفاصيل البيبلوغرافية
العنوان: Assessing the psychometric properties of the French WHOQOL-HIV BREF within the ANRS CO3 Aquitaine Cohort’s QuAliV ancillary study
المؤلفون: Diana Barger, Mojgan Hessamfar, Didier Neau, Marc-Olivier Vareil, Estibaliz Lazaro, Pierre Duffau, Nicolas Rouanes, Olivier Leleux, Fabien Le Marec, Marie Erramouspe, Linda Wittkop, François Dabis, Fabrice Bonnet
المصدر: Health and Quality of Life Outcomes, Vol 18, Iss 1, Pp 1-14 (2020)
بيانات النشر: BMC, 2020.
سنة النشر: 2020
المجموعة: LCC:Computer applications to medicine. Medical informatics
مصطلحات موضوعية: HIV, Health-related quality of life, WHOQOL-HIV BREF, Computer applications to medicine. Medical informatics, R858-859.7
الوصف: Abstract Background Antiretroviral therapy has prolonged the lives of those with human immunodeficiency virus (HIV), but the effects of chronic infection on their health-related quality of life (HRQoL) remain a concern. Numerous instruments have been developed to measure HRQoL, yet evidence of their cross-cultural equivalence and continued applicability is limited. We adapted the WHOQOL-HIV BREF to French and assessed its psychometric properties in a sample of community-dwelling adults living with HIV who were mostly virally suppressed. Methods We conducted a cross-sectional study within the ANRS CO3 Aquitaine cohort from July 2018 to May 2019. Five hundred eighty-six participants were consecutively enrolled at their HIV-consultations and completed either a web-based (n = 406) or paper self-administered assessment (n = 180). The means and standard deviations for items and domains were computed and the presence of floor and ceiling effects assessed. We evaluated internal consistency by calculating Cronbach’s alpha coefficients per domain. We assessed construct validity by performing a Confirmatory Factor Analysis (CFA). Concurrent, convergent and discriminant validity were assessed with Pearson’s correlations and known-group validity was assessed according to CD4 cell count, viral load, Centers for Disease Control and Prevention clinical categories for HIV, and hospitalization of more than 48 h within 2 years of the most recent consultation using one-way analysis of variance and independent t-tests. Results Five hundred eighty-six PLWH were included in this analysis. Their median age was 55; 73% were male; 85% were of French descent; 99% were on ART and 93% were virally suppressed. We found floor effects for one and ceiling effects for 11 items. Four of the six domains showed good internal consistency (α range: 0.63–0.79). CFA showed that the WHOQOL-HIV BREF’s six-domain structure produced an acceptable fit (SRMR = 0.059; CFI = 0.834; RMSEA = 0.07; 90% CI: 0.06–0.08). It showed good concurrent, convergent and discriminant validity. There was some evidence of known-group validity. The personal beliefs domain had the highest score (15.04 ± 3.35) and the psychological health domain had the lowest (13.70 ± 2.78). Conclusions The French WHOQOL-HIV BREF has acceptable measurement properties. Its broad conceptualisation of HRQoL, going beyond physical and mental health, may be of particular value in our older, treatment-experienced and virally suppressed population. Trial registration ClinicalTrials.gov NCT03296202 (Archived by WebCite at http://www.webcitation.org/6zgOBArps ).
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1477-7525
Relation: http://link.springer.com/article/10.1186/s12955-020-01451-8; https://doaj.org/toc/1477-7525
DOI: 10.1186/s12955-020-01451-8
URL الوصول: https://doaj.org/article/155e6bce1c41478291d25c828cc7bb6c
رقم الانضمام: edsdoj.155e6bce1c41478291d25c828cc7bb6c
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14777525
DOI:10.1186/s12955-020-01451-8