التفاصيل البيبلوغرافية
| العنوان: |
A study of clinical and serological correlation of early myocardial injury in elderly patients infected with the Omicron variant |
| المؤلفون: |
Xueying Yu, Xiaoguang Li, Shuai Xia, Lu Lu, Jiahui Fan, Ying Wang, Yan Fu, Chen Suo, Qiuhong Man, Lize Xiong |
| المصدر: |
Frontiers in Cardiovascular Medicine, Vol 11 (2024) |
| بيانات النشر: |
Frontiers Media S.A., 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: |
Omicron variant, elderly, myocardial injury, clinical characteristics, risk factors, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: |
IntroductionMyocardial injury in elderly Omicron variant patients is a leading cause of severe disease and death. This study focuses on elucidating the clinical characteristics and potential risk factors associated with myocardial injury in elderly patients infected with the Omicron variant.MethodsMyocardial injury was defined based on elevated cardiac troponin concentrations exceeding the 99th percentile upper reference limit. Among 772 elderly Omicron-infected patients, categorized into myocardial injury (n = 263) and non-myocardial injury (n = 509) groups. The stratified log-rank statistic was used to compare the probability of patients developing intensive care. Receiver operating characteristic curves were used to determine the best cut-off values of clinical and laboratory data for predicting myocardial injury. Univariate and multivariate logistic regression was adopted to analyze the risk factors for myocardial injury.ResultsThe occurrence of myocardial injury in Omicron variant-infected geriatric patients was up to 34.07% and these patients may have a higher rate of requiring intensive care (P 22.69 pg/ml, procalcitonin > 0.0435 ng/ml, D-dimer > 0.615 mg/L, and sCr > 81.30 μmol/L.ConclusionThis study revealed the clinical characteristics and potential risk factors associated with myocardial injury that enable early diagnosis of myocardial injury in Omicron variant-infected elderly patients, providing important reference indicators for early diagnosis and timely clinical intervention. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2297-055X |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fcvm.2024.1268499/full; https://doaj.org/toc/2297-055X |
| DOI: |
10.3389/fcvm.2024.1268499 |
| URL الوصول: |
https://doaj.org/article/152ba04fd9774b9db4c077c525f377d8 |
| رقم الانضمام: |
edsdoj.152ba04fd9774b9db4c077c525f377d8 |
| قاعدة البيانات: |
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