Academic Journal

IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population

التفاصيل البيبلوغرافية
العنوان: IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population
المؤلفون: Daniele C. Nascimento, Paulo H. Melo, Annie R. Piñeros, Raphael G. Ferreira, David F. Colón, Paula B. Donate, Fernanda V. Castanheira, Aline Gozzi, Paula G. Czaikoski, Wanda Niedbala, Marcos C. Borges, Dario S. Zamboni, Foo Y. Liew, Fernando Q. Cunha, Jose C. Alves-Filho
المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
بيانات النشر: Nature Portfolio, 2017.
سنة النشر: 2017
المجموعة: LCC:Science
مصطلحات موضوعية: Science
الوصف: Patients who survive sepsis are at increased risk of infection owing to long-term immunosuppression that is associated with an increase in Treg cell numbers. Here the authors show expansion of the Treg cell population in sepsis mice is driven by IL-33-induced ILC2 activation of IL-10 production by macrophages.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/ncomms14919
URL الوصول: https://doaj.org/article/14c052279c2943bbbeef427db07d64ab
رقم الانضمام: edsdoj.14c052279c2943bbbeef427db07d64ab
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20411723
DOI:10.1038/ncomms14919