التفاصيل البيبلوغرافية
العنوان: |
Impact of brief prewarming on anesthesia-related core-temperature drop, hemodynamics, microperfusion and postoperative ventilation in cytoreductive surgery of ovarian cancer: a randomized trial |
المؤلفون: |
L. Kaufner, P. Niggemann, T. Baum, S. Casu, J. Sehouli, A. Bietenbeck, M. Boschmann, C. D. Spies, A. Henkelmann, C. von Heymann |
المصدر: |
BMC Anesthesiology, Vol 19, Iss 1, Pp 1-10 (2019) |
بيانات النشر: |
BMC, 2019. |
سنة النشر: |
2019 |
المجموعة: |
LCC:Anesthesiology |
مصطلحات موضوعية: |
Prewarming, Ovarian cancer, Microperfusion, Normothermia, Anesthesiology, RD78.3-87.3 |
الوصف: |
Abstract Background General (GA)- and epidural-anesthesia may cause a drop in body-core-temperature (BCTdrop), and hypothermia, which may alter tissue oxygenation (StO2) and microperfusion after cytoreductive surgery for ovarian cancer. Cell metabolism of subcutaneous fat- or skeletal muscle cells, measured in microdialysis, may be affected. We hypothesized that forced-air prewarming during epidural catheter placement and induction of GA maintains normothermia and improves microperfusion. Methods After ethics approval 47 women scheduled for cytoreductive surgery were prospectively enrolled. Women in the study group were treated with a prewarming of 43 °C during epidural catheter placement. BCT (Spot on®, 3 M) was measured before (T1), after induction of GA (T2) at 15 min (T3) after start of surgery, and until 2 h after ICU admission (TICU2h). Primary endpoint was BCTdrop between T1 and T2. Microperfusion-, hemodynamic- and clinical outcomes were defined as secondary outcomes. Statistical analysis used the Mann-Whitney-U- and non-parametric-longitudinal tests. Results BCTdrop was 0.35 °C with prewarming and 0.9 °C without prewarming (p |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
1471-2253 |
Relation: |
http://link.springer.com/article/10.1186/s12871-019-0828-1; https://doaj.org/toc/1471-2253 |
DOI: |
10.1186/s12871-019-0828-1 |
URL الوصول: |
https://doaj.org/article/14bf359d9dc8409785a37cc448e8b640 |
رقم الانضمام: |
edsdoj.14bf359d9dc8409785a37cc448e8b640 |
قاعدة البيانات: |
Directory of Open Access Journals |