التفاصيل البيبلوغرافية
| العنوان: |
Numerical Investigation of Axonal Damage for Regular and Irregular Axonal Distributions |
| المؤلفون: |
Morteza Kazempour, Amin Kazempour, Majid Baniassadi, Yves Remond, Mostafa Baghani |
| المصدر: |
Frontiers in Mechanical Engineering, Vol 7 (2021) |
| بيانات النشر: |
Frontiers Media S.A., 2021. |
| سنة النشر: |
2021 |
| المجموعة: |
LCC:Mechanical engineering and machinery |
| مصطلحات موضوعية: |
visco-hyperelastic, traumatic brain injury (TBI), diffuse axonal injury (DAI), FEM, axonal damage, Mechanical engineering and machinery, TJ1-1570 |
| الوصف: |
Recently, various researches have revealed the importance of the investigations performed for evaluating mechanical properties and damages of the brain tissues while dealing with the production of surgical ligaments and helmets. Therefore, it is vital to study the structure of the brain both experimentally and numerically. By experimental tests, despite being costly, it is almost impossible to establish stress distribution in micro scale, which causes injury. Micromechanical predictions are effective ways to assess brain behavior. They can be applied to compensate for some experimental test limitations. In this work, a numerical study of the axonal injury in different heterogeneous porcine brain parts with different axon distributions under quasi-static loading is provided. In order to produce a heterogeneous structure, axons are distributed in regular, semi-regular, and irregular patterns inside the representative volume element. To accurately examine the brain tissue time-dependent behavior, a visco-hyperelastic constitutive model is developed. Also, axonal damage is studied under different conditions by applying different levels of load and rate. Because of geometrical complexities, a self-consistent method was applied to study the damage in higher volume fractions of the axon. The results reveal that the regions of the brain enjoying a regular axon distribution would have higher strength. In addition, among the two influential load and loading rate parameters, the brain tissue in all regions shows more sensitivity toward the applying load. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2297-3079 |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fmech.2021.685519/full; https://doaj.org/toc/2297-3079 |
| DOI: |
10.3389/fmech.2021.685519 |
| URL الوصول: |
https://doaj.org/article/13ed06a79599440e972c62801476a4b3 |
| رقم الانضمام: |
edsdoj.13ed06a79599440e972c62801476a4b3 |
| قاعدة البيانات: |
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