Academic Journal
Chemistry and bioactivities of natural steroidal alkaloids
| العنوان: | Chemistry and bioactivities of natural steroidal alkaloids |
|---|---|
| المؤلفون: | Mei-Ling Xiang, Bin-Yuan Hu, Zi-Heng Qi, Xiao-Na Wang, Tian-Zhen Xie, Zhao-Jie Wang, Dan-Yu Ma, Qi Zeng, Xiao-Dong Luo |
| المصدر: | Natural Products and Bioprospecting, Vol 12, Iss 1, Pp 1-50 (2022) |
| بيانات النشر: | SpringerOpen, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Botany |
| مصطلحات موضوعية: | Steroidal alkaloids, Chemistry, Bioactivities, Solanaceae, Liliaceae, Apocynaceae, Botany, QK1-989 |
| الوصف: | Abstract Steroidal alkaloids possess the basic steroidal skeleton with a nitrogen atom in rings or side chains incorporated as an integral part of the molecule. They have demonstrated a wide range of biological activities, and some of them have even been developed as therapeutic drugs, such as abiraterone acetate (Zytiga®), a blockbuster drug, which has been used for the treatment of prostate cancer. Structurally diverse natural steroidal alkaloids present a wide spectrum of biological activities, which are attractive for natural product chemistry and medicinal chemistry communities. This review comprehensively covers the structural classification, isolation and various biological activities of 697 natural steroidal alkaloids discovered from 1926 to October 2021, with 363 references being cited. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2192-2195 2192-2209 |
| Relation: | https://doaj.org/toc/2192-2195; https://doaj.org/toc/2192-2209 |
| DOI: | 10.1007/s13659-022-00345-0 |
| URL الوصول: | https://doaj.org/article/1180fbdece7046c98b897626023410f9 |
| رقم الانضمام: | edsdoj.1180fbdece7046c98b897626023410f9 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 21922195 21922209 |
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| DOI: | 10.1007/s13659-022-00345-0 |