التفاصيل البيبلوغرافية
| العنوان: |
Estimates of vaccine effectiveness of the updated monovalent XBB.1.5 COVID-19 vaccine against symptomatic SARS-CoV-2 infection, hospitalization, and receipt of oxygen therapy in South Korea - October 26 to December 31, 2023 |
| المؤلفون: |
Jung Ah Lee, Heeseon Jang, Sang Min Ahn, Jae Eun Seong, Young Keun Kim, Yujin Sohn, Sook In Jung, Hye Won Jeong, Shin-Woo Kim, Jin-Soo Lee, Ji-Hyeon Baek, Se Ju Lee, Geun-Yong Kwon, Jeeyeon Shin, Hangjin Jeong, Changsoo Kim, Jun Yong Choi |
| المصدر: |
International Journal of Infectious Diseases, Vol 148, Iss , Pp 107249- (2024) |
| بيانات النشر: |
Elsevier, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: |
COVID-19, Vaccine, Vaccine effectiveness, XBB.1.5, Infectious and parasitic diseases, RC109-216 |
| الوصف: |
Objectives: We evaluated the vaccine effectiveness of monovalent XBB.1.5 vaccine against symptomatic COVID-19 infection, hospitalization, and the need for oxygen therapy in South Korea. Design: This study employed a test-negative case-control design. COVID-19 test results in symptomatic subjects from six university hospitals across South Korea were collected (October 26–December 31, 2023). The adjusted absolute and relative vaccine effectiveness were assessed. Results: In total, 5516 subjects were enrolled: 4,824 were unvaccinated with XBB.1.5, and 692 were vaccinated with XBB.1.5 COVID-19 mRNA vaccines. The absolute vaccine effectiveness when comparing the odds between XBB.1.5 vaccination and no vaccination against symptomatic COVID-19 infection, hospitalization, and oxygen therapy was 65.2% (95% CI, 36.1-81.0), 77.3% (95% CI, 51.1-89.5), and 85.3% (95% CI, 57.8-94.9), respectively. The relative vaccine effectiveness when comparing the odds between XBB.1.5 vaccination and no XBB.1.5 vaccination against symptomatic COVID-19 infection, hospitalization, and oxygen therapy was 57.7% (95% CI, 34.7-72.6), 64.3% (95% CI, 35.9-80.2), and 65.5% (95% CI, 27.0-83.7), respectively. Conclusion: The short-term effectiveness of the XBB.1.5 vaccine against symptomatic COVID-19 infection, hospitalization, and receipt of oxygen therapy in South Korea was significant. Long-term vaccine effectiveness warrants evaluation, and these assessments should be conducted regularly. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1201-9712 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S1201971224003205; https://doaj.org/toc/1201-9712 |
| DOI: |
10.1016/j.ijid.2024.107249 |
| URL الوصول: |
https://doaj.org/article/d1000e63cd0a44a3995d31dac7e3536f |
| رقم الانضمام: |
edsdoj.1000e63cd0a44a3995d31dac7e3536f |
| قاعدة البيانات: |
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