التفاصيل البيبلوغرافية
| العنوان: |
Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation |
| المؤلفون: |
Yi-Ing Chen, Chin-Chun Chang, Min-Fen Hsu, Yung-Ming Jeng, Yu-Wen Tien, Ming-Chu Chang, Yu-Ting Chang, Chun-Mei Hu, Wen-Hwa Lee |
| المصدر: |
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022) |
| بيانات النشر: |
Nature Portfolio, 2022. |
| سنة النشر: |
2022 |
| المجموعة: |
LCC:Science |
| مصطلحات موضوعية: |
Science |
| الوصف: |
Direct contact between tumour cells and fibroblasts influences tumour cell behaviour. Here the authors show that pancreatic cancer cells and fibroblasts directly interact via homophilic ATP1A1 binding, which induces fibroblasts to secrete activin A to promote epithelial-mesenchymal transition of tumour cells and myofibroblast activation. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-022-30638-4 |
| URL الوصول: |
https://doaj.org/article/0ef09420616e4351be36b283dc768cbd |
| رقم الانضمام: |
edsdoj.0ef09420616e4351be36b283dc768cbd |
| قاعدة البيانات: |
Directory of Open Access Journals |
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