Academic Journal

Potential Misdiagnosis between COVID-19 and Dengue Infection Using Rapid Serological Test

التفاصيل البيبلوغرافية
العنوان: Potential Misdiagnosis between COVID-19 and Dengue Infection Using Rapid Serological Test
المؤلفون: Siti Qamariyah Khairunisa, Ilham Harlan Amarullah, Siti Churrotin, Anisa Lailatul Fitria, Mochammad Amin, Maria Inge Lusida, Soegeng Soegijanto
المصدر: Infectious Disease Reports, Vol 13, Iss 2, Pp 540-551 (2021)
بيانات النشر: MDPI AG, 2021.
سنة النشر: 2021
المجموعة: LCC:Other systems of medicine
مصطلحات موضوعية: cross-reactivity, COVID-19, Sars-Cov 2, dengue, rapid serological test, Other systems of medicine, RZ201-999
الوصف: The coronavirus disease 2019 (COVID-19) pandemic that has a significant rapid transmission is an international public health concern. Several dengue-endemic countries reported similar clinical and laboratory features between COVID-19 and dengue in the early incubation period, and thus discerning the infection is difficult. As a dengue-endemic country, Indonesia also poses the same challenge during the COVID-19 outbreak. This current study analyzed the IgG and IgM profiles from COVID-19 patients by using a serological SARS-CoV-2 and dengue rapid test. In addition, 38 sera from healthy individuals (pre-COVID-19 date) were analyzed using a dengue rapid test. Among 120 samples, 4 samples indicated dengue IgG positive. However, IgM, NS1, and RT-PCR analyses showed negative results. Interestingly, regarding seropositivity of NS1 and DENV IgG from healthy individuals (pre COVID-19 infection), two samples were positive DENV IgG, while one of them was positive NS1. This suggested that in the dengue-endemic area, many people have already experienced dengue and have immunity against dengue virus. There is also the possibility of antibody cross-reactivity between COVID-19 and dengue infection. This also emphasizes the high demand for a rapid method with high sensitivity and specificity that can distinguish between SARS-CoV-2 and dengue.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2036-7449
Relation: https://www.mdpi.com/2036-7449/13/2/50; https://doaj.org/toc/2036-7449
DOI: 10.3390/idr13020050
URL الوصول: https://doaj.org/article/0edbeb45572e4db5ac0b3e1dc72921d4
رقم الانضمام: edsdoj.0edbeb45572e4db5ac0b3e1dc72921d4
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20367449
DOI:10.3390/idr13020050