Academic Journal
Effect of fasting glucose levels on carotid intima-media thickness in premenopausal versus postmenopausal women
| العنوان: | Effect of fasting glucose levels on carotid intima-media thickness in premenopausal versus postmenopausal women |
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| المؤلفون: | Ren Xia, Su Fan, Hu Jian, Cao Lei, Mei Wendan, Wang Chenxu, Fang Yicheng, Grace Tavengana, Jiang Mingfei, Wu Huan, Wen Yufeng |
| المصدر: | Archives of Endocrinology and Metabolism, Vol 68 (2024) |
| بيانات النشر: | Brazilian Society of Endocrinology and Metabolism, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine LCC:Diseases of the endocrine glands. Clinical endocrinology |
| مصطلحات موضوعية: | Postmenopause, premenopause, carotid intima-media thickness, fasting blood glucose, Medicine, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
| الوصف: | ABSTRACT Objective: To investigate the relationship between fasting blood glucose (FBG) and carotid intima-media thickness (IMT) in premenopausal and postmenopausal women. Subjects and methods: The study enrolled 2,959 women seen at the Maanshan People's Hospital of Anhui Province from December 2013 to December 2018. Carotid IMT was measured using Doppler ultrasound. Linear regression and R smoothing curves were used to analyze the relationship between blood glucose level and carotid IMT in the premenopausal and postmenopausal groups. Results: Postmenopausal compared with premenopausal women had higher mean IMT (mIMT; 0.81 ± 0.23 mm versus 0.70 ± 0.14 mm, respectively, p < 0.001) and maximum IMT (maxIMT; 0.86 ± 0.35 mm versus 0.74 ± 0.16 mm, respectively, p < 0.001) values. On linear regression analysis, mIMT values increased with increasing FBG values when FBG level was ≤ 7 mmol/L, but no significance was found between FBG and maxIMT. After stratification by menopausal status, mIMT and maxIMT increased with increasing FBG when FBG was ≤ 7 mmol/L in the premenopausal group. In the postmenopausal group, mIMT and maxIMT increased with increasing FBG. After adjustment for covariate factors, the relationship between FBG and mIMT remained the same as before the adjustment, but when FBG was ≤ 11 mmol/L, the maxIMT increased with increasing FBG. In the stratification analysis, maxIMT increased with increasing FBG when FBG was ≤ 7 mmol/L in the premenopausal group, while both mIMT and maxIMT increased with increasing FBG when FBG was > 10 mmol/L in the postmenopausal group. Conclusion: Levels of FBG contributed more to increased IMT in postmenopausal than premenopausal women. The influence of FBG was greater on maxIMT than mIMT. Additionally, FBG was helpful in assessing focal thickening of the carotid intima. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2359-4292 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972024000100324&lng=en&tlng=en; http://www.scielo.br/pdf/aem/v68/2359-4292-aem-68-e230110.pdf; https://doaj.org/toc/2359-4292 |
| DOI: | 10.20945/2359-4292-2023-0110 |
| URL الوصول: | https://doaj.org/article/0daf9e959d724631862f3e8508db580f |
| رقم الانضمام: | edsdoj.0daf9e959d724631862f3e8508db580f |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23594292 |
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| DOI: | 10.20945/2359-4292-2023-0110 |